Results 151 to 160 of about 36,903 (217)

Paediatric Phase I/II Clinical Trial Assessments Under the New EU Clinical Trial Regulation: A Descriptive Analysis. [PDF]

Pharmaceut Med
Fankhauser L, Ligas F, Lesa G, Karlsen AS, Lunzer M, Al M, Scherer S, Benchetrit S, Riedel C, Kopp-Schneider A, Witt R, Witt O, Karres D, van Tilburg CM.   +13 more
europepmc   +1 more source

Broader Familial Cancer Risk in Relatives of Testicular Cancer Patients: Insights From Two Mediterranean Populations

Andrology, EarlyView.
ABSTRACT Background Familial clustering of testicular germ cell tumour (TGCT) is well‐established, whereas the risk of non‐testicular cancer among relatives remains inconsistent across studies. Objective To evaluate the overall and site‐specific cancer risk among first‐degree relatives and grandparents of TGCT patients compared to cancer‐free controls.
Csilla Krausz, Chiara Abrardo, Viktoria Rosta, Daniel Moreno‐Mendoza, Luca Bressan, Matteo Vannucci, Rebecca Passerotti, Arianna Meacci, Ginevra Farnetani, Viola Bonini, Giovanni Corona, Maria Grazia Fino, Eduard Ruiz‐Castañé, Antoni Riera‐Escamilla   +13 more
wiley   +1 more source

Prenatal phenotypes and pregnancy outcomes of fetuses with recurrent 16p13.11 microduplications. [PDF]

Medicine (Baltimore)
Xu T, Yue F, Ge Y, Liu R.
europepmc   +1 more source

Navigating Ethical Review Processes in Conflict‐Affected, Authoritarian Contexts: A Case Study of Myanmar's Interim Ethics Review Board (IERB)

Asia Pacific Viewpoint, EarlyView.
ABSTRACT This article examines the formation and operation of Myanmar's Interim Ethics Review Board (IERB), which was established in November 2023 by displaced academics involved in the Civil Disobedience Movement against the 2021 military coup. Operating within a highly repressive, conflict‐ridden environment, the IERB exemplifies a locally‐led and ...
Phyu Phyu Thin Zaw, Su Su Maw, Nyein Chan, The Spring IERB Team   +3 more
wiley   +1 more source

Sample size determination for hypothesis testing on the intraclass correlation coefficient in a two‐way analysis of variance model

British Journal of Mathematical and Statistical Psychology, EarlyView.
Abstract Reliability evaluation is critical in fields such as psychology and medicine to ensure accurate diagnosis and effective treatment management. When participants are evaluated by the same raters, a two‐way ANOVA model is suitable to model the data, with the intraclass correlation coefficient (ICC) serving as the reliability metric.
Dipro Mondal, Alberto Cassese, Math J. J. M. Candel, Sophie Vanbelle   +3 more
wiley   +1 more source

Distinct molecular and tumor microenvironment characteristics of mucinous adenocarcinoma in colorectal cancer. [PDF]

iScience
Li J, Fu Y, Bai F, Wu Z, Qin G, Deng Y.
europepmc   +1 more source

Gasdermin‐Mediated Pyroptosis: Novel Strategies Against Colorectal Cancer

Cancer Science, EarlyView.
Pyroptosis is a double‐edged sword in colorectal cancer (CRC): chronic low‐grade pyroptosis promotes tumor progression, whereas acute induction of pyroptosis in cancer cells triggers antitumor immunity and enhances therapeutic response. Targeting gasdermin‐mediated pyroptosis represents a promising strategy for CRC treatment.
Kaibo Guo, Yuqian Feng, Jiamin Lu, Nuerbiye Abudurexiti, Xinlei Zhou, Mengfan Wei, Song Zheng   +6 more
wiley   +1 more source

Mutations Targeted by Nous-209 Immunotherapy Occur Early in Lynch Syndrome Carriers' Precancer Lesions with Microsatellite Instability. [PDF]

Cancer Prev Res (Phila)
Micarelli E, De Marco L, Spaggiari P, D'Alise AM, Dal Buono A, Menini M, Giatti V, D'Aprano A, Scarselli E, Hassan C, Repici A.   +10 more
europepmc   +1 more source

RotGS: Rotation‐Guided 3D Gaussian Splatting for Turntable Sequences without Structure‐from‐Motion

Computer Graphics Forum, EarlyView.
Abstract The field of 3D reconstruction from multi‐view images has advanced rapidly thanks to 3D Gaussian Splatting (3DGS), which enables efficient and photorealistic scene representation. However, optimizing 3DGS requires high‐quality images from various viewpoints with accurate camera poses.
Kyumin Kim, Dohae Lee, Hanul Baek, In‐Kwon Lee   +3 more
wiley   +1 more source

MLH1 promoter methylation-induced dMMR/MSS in endometrial cancer: case report. [PDF]

Discov Oncol
Qu Z, Mao J, Zhang X, Xiang L.
europepmc   +1 more source