Results 1 to 10 of about 1,821 (159)

Selective killing of human immunodeficiency virus infected cells by non-nucleoside reverse transcriptase inhibitor-induced activation of HIV protease

Retrovirology, 2010
BackgroundCurrent antiretroviral therapy against human immunodeficiency virus (HIV-1) reduces viral load and thereby prevents viral spread, but it cannot eradicate proviral genomes from infected cells.
D. Jochmans, Maria Anders, I. Keuleers, Liesbet Smeulders, H. Kräusslich, G. Kraus, B. Müller   +6 more
semanticscholar   +1 more source

17β-estradiol-containing liposomes as a novel delivery system for the antisense therapy of ER-positive breast cancer: An in vitro study on the MCF-7 cell line.

Oncology Report, 2015
Z. Heger, J. Gumulec, Natalia Cernei, Katerina Tmejova, Pavel Kopel, J. Balvan, M. Masařík, O. Zítka, M. Beklova, V. Adam, R. Kizek   +10 more
semanticscholar   +1 more source

Graphene-Based Nanosystem for Targeted Delivery of Anti-Sense miRNA-21 on Hepatocellular Carcinoma Cells. [PDF]

Int J Mol Sci
Trischitta P, Kucharzewska P, Nasiłowska B, Skrzeczanowski W, Pennisi R, Sciortino MT, Kutwin M.   +6 more
europepmc   +1 more source

Cell-penetrating antibody enhances nuclear delivery of triplex-forming oligonucleotides targeting HER2-positive cancers. [PDF]

Mol Ther Nucleic Acids
Minnah A, García Tubéns NM, Krysztofiak A, Liu Y, Glazer PM, Rogers FA.   +5 more
europepmc   +1 more source

Decoding the genetic blueprints of neurological disorders: disease mechanisms and breakthrough gene therapies. [PDF]

Front Neurol
Saeed U, Piracha ZZ, Tariq MN, Syed S, Rauf M, Razaq L, Iftikhar MK, Maqsood A, Ahsan SM.   +8 more
europepmc   +1 more source

The role of exosomes as oligonucleotide delivery system for managing α-synuclein in Parkinson's disease: A systematic review of <i>in vivo</i> studies. [PDF]

Mol Ther Nucleic Acids
Salarpour S, Dourandish F, Salajegheh A, Hashemi S.   +3 more
europepmc   +1 more source

Advances in gene therapy for mitochondrial genetic disorders: current status and clinical implementation challenges. [PDF]

J Transl Med
Lyu L, Qie B, He Y, Chen F, Liu B.
europepmc   +1 more source

Can Gene Therapy Transform the Treatment Landscape of Posterior Segment Eye Diseases? A Comprehensive Review of Recent Advancements. [PDF]

Drugs
Chen KY, Chan HC, Chan CM.
europepmc   +1 more source

Tau-Targeted Therapeutic Strategies: Mechanistic Targets, Clinical Pipelines, and Analysis of Failures. [PDF]

Cells
Shen X, Li H, Zhang B, Li Y, Zhu Z.
europepmc   +1 more source

Human-Induced Pluripotent Stem Cell Models for Amyloid Cardiomyopathy: From Mechanistic Insights to Therapeutic Discovery. [PDF]

J Cardiovasc Dev Dis
Liu Y, Riaz M.
europepmc   +1 more source