Results 1 to 10 of about 1,427 (69)

Advances in Nucleic Acid Research: Exploring the Potential of Oligonucleotides for Therapeutic Applications and Biological Studies. [PDF]

Int J Mol Sci, 2023
Moccia M, Pascucci B, Saviano M, Cerasa MT, Terzidis MA, Chatgilialoglu C, Masi A.   +6 more
europepmc   +1 more source

Decoding the genetic blueprints of neurological disorders: disease mechanisms and breakthrough gene therapies. [PDF]

Front Neurol
Saeed U, Piracha ZZ, Tariq MN, Syed S, Rauf M, Razaq L, Iftikhar MK, Maqsood A, Ahsan SM.   +8 more
europepmc   +1 more source

Site-blocking antisense oligonucleotides as a mechanism to fine-tune MeCP2 expression. [PDF]

RNA
Vanderplow AM, Dodis GE, Rhee Y, Cikowski JJ, Gonzalez S, Smith ML, Gogliotti RG.   +6 more
europepmc   +1 more source

Transforming cancer treatment: integrating patient-derived organoids and CRISPR screening for precision medicine. [PDF]

Front Pharmacol
Zhu Z, Shen J, Ho PC, Hu Y, Ma Z, Wang L.   +5 more
europepmc   +1 more source

MicroRNA in cancer therapy: breakthroughs and challenges in early clinical applications. [PDF]

J Exp Clin Cancer Res
Martino MTD, Tagliaferri P, Tassone P.
europepmc   +1 more source

Engineered mitochondria in diseases: mechanisms, strategies, and applications. [PDF]

Signal Transduct Target Ther
Li M, Wu L, Si H, Wu Y, Liu Y, Zeng Y, Shen B.   +6 more
europepmc   +1 more source

Consensus guidelines for assessing eligibility of pathogenic DNA variants for antisense oligonucleotide treatments. [PDF]

Am J Hum Genet
Cheerie D, Meserve MM, Beijer D, Kaiwar C, Newton L, Taylor Tavares AL, Verran AS, Sherrill E, Leonard S, Sanders SJ, Blake E, Elkhateeb N, Gandhi A, Liang NSY, Morgan JT, Verwillow A, Verheijen J, Giles A, Williams S, Chopra M, Croft L, Dafsari HS, Davidson AE, Friedman J, Gregor A, Haque B, Lechner R, Montgomery KA, Ryten M, Schober E, Siegel G, Sullivan PJ, Whittle EF, Zardetto B, Yu TW, Synofzik M, Aartsma-Rus A, Costain G, Lauffer MC, N=1 Collaborative.   +39 more
europepmc   +1 more source

Functional Nucleic Acid Nanostructures for Mitochondrial Targeting: The Basis of Customized Treatment Strategies. [PDF]

Molecules
He W, Dong S, Zeng Q.
europepmc   +1 more source

Targeting Regulatory Noncoding RNAs in Human Cancer: The State of the Art in Clinical Trials. [PDF]

Pharmaceutics
Piergentili R, Sechi S.
europepmc   +1 more source

From dysfunction to healing: advances in mitochondrial therapy for Osteoarthritis. [PDF]

J Transl Med
Zhang M, Wu J, Cai K, Liu Y, Lu B, Zhang J, Xu J, Gu C, Chen T.   +8 more
europepmc   +1 more source