Results 131 to 140 of about 1,526 (167)

In Silico Design of Novel EpCAM-Binding Aptamers for Targeted Delivery of RNA Therapeutics. [PDF]

Nanomaterials (Basel)
Driscoll J, Gondaliya P, Ziemer A, Yan IK, Gupta Y, Patel T.   +5 more
europepmc   +1 more source

The Introduction of Extended Out‐of‐Home Care (OOHC) Until 21 Years in Australia: A Mapping of Policy, Legislation and Programs in Each Jurisdiction

Australian Journal of Social Issues, EarlyView.
ABSTRACT It is increasingly recognised by global research that extending out‐of‐home care (OOHC) until at least 21 years of age is the policy reform most likely to advance improved outcomes for care leavers. In recent years, all eight Australian jurisdictions (States and Territories) have introduced forms of extended care programs.
Philip Mendes, Steven Roche, Isabella Kristo, Melissa O'Donnell, Tim Moore, Catia Malvaso, Jemma Venables, Joseph McDowall   +7 more
wiley   +1 more source

Macrocyclic Peptide Probes for Immunomodulatory Protein CD59: Potent Modulators of Bacterial Toxin Activity and Antibody‐Dependent Cytotoxicity

Angewandte Chemie, EarlyView.
This study presents novel macrocyclic peptides with low nanomolar affinity for CD59, an immunomodulatory cell surface receptor associated with human disease. Crystallographic and structure‐activity relationship (SAR) studies reveal peptide CP‐06 mimics the binding of biologically relevant CD59 interaction partners. Dimeric and lipidated CP‐06 analogues
Jasmine K. Bickel, Ammar. I. S. Ahmed, Aidan B. Pidd, Rhodri M. Morgan, Tom E. McAllister, Sam Horrell, Emma C. Couves, Hemavathi Nagaraj, Edward J. Bartlett, Kamel El Omari, Akane Kawamura, Doryen Bubeck, Edward W. Tate   +12 more
wiley   +2 more sources

Harnessing endogenous miRNA targeting ZIKV: A cutting-edge strategy to inhibit virus infection. [PDF]

Mol Ther Nucleic Acids
Rosa RSM, Palameta S, Toscaro JM, Miller ME, Lopes-de-Oliveira PS, Bajgelman MC.   +5 more
europepmc   +1 more source

Current State of Therapeutics for HTLV-1. [PDF]

Viruses
Wang TT, Hirons A, Doerflinger M, Morris KV, Ledger S, Purcell DFJ, Kelleher AD, Ahlenstiel CL.   +7 more
europepmc   +1 more source

Dual‐energy X‐ray absorptiometry for detecting neurogenic pulmonary edema in a mouse model of subarachnoid hemorrhage

Animal Models and Experimental Medicine, EarlyView.
Using a murine model of SAH, brain magnetic resonance imaging (MRI) was performed to confirm subarachnoid clot formation in the T2*‐weighted images sequence (left). Chest micro‐CT and DXA were performed to measure, respectively, the Hounsfield units (HU) and lean mass (LM) (middle) in order to test their relationship and ability to detect post‐SAH NPE (
Tatsushi Mutoh, Hiroaki Aono, Yushi Mutoh, Tatsuya Ishikawa   +3 more
wiley   +1 more source

In vitro assessment of the effect of magnetic fields on efficacy of biosynthesized selenium nanoparticles by Alborzia kermanshahica. [PDF]

BMC Biotechnol
Eydelkhani M, Kiabi S, Nowruzi B.
europepmc   +1 more source

Gene therapy for retinal diseases: From genetics to treatment. [PDF]

Indian J Ophthalmol
Khaparde A, Mathias GP, Poornachandra B, Thirumalesh MB, Shetty R, Ghosh A.   +5 more
europepmc   +1 more source

uORF-targeting steric block antisense oligonucleotides do not reproducibly increase RNASEH1 expression. [PDF]

Mol Ther Nucleic Acids
Ahlskog N, Svrzikapa N, Abuhamdah R, Kye M, Jad Y, Feng N, Hanson B, Wood MJA, Roberts TC.   +8 more
europepmc   +1 more source

An Update: Enzymatic Synthesis for Industrial Applications

Angewandte Chemie International Edition, EarlyView.
Biocatalysis has become a sustainable and cost‐competitive alternative to established chemical synthesis, enabling the enzyme‐based production of not only commodity chemicals but (non‐natural) amino acids, (rare) sugars, as well as synthetic nucleotides.
Thomas Bayer, Shuke Wu, Radka Snajdrova, Kai Baldenius, Uwe T. Bornscheuer   +4 more
wiley   +1 more source