Results 41 to 50 of about 11,174 (173)

Health System Resilience and Afghan Refugee Health in Pakistan: An Exploratory Study of Challenges and Pathways to Inclusion

open access: yesThe International Journal of Health Planning and Management, EarlyView.
ABSTRACT Pakistan has hosted Afghan refugees for more than four decades, in one of the world's most protracted displacements of people. Afghan refugees receive health services through United Nations High Commissioner for Refugees (UNHCR) and non‐governmental organisation (NGO) supported programmes alongside public sector facilities at every tier.
Zahid Ali Memon   +4 more
wiley   +1 more source

Estimating Hierarchical Demand in Retail Operations

open access: yesJournal of Operations Management, EarlyView.
ABSTRACT A hierarchical structure over product attributes is a central input to many product assortment and inventory optimization models, yet no existing method can recover such structures from the aggregate sales data that retailers routinely collect.
Blair Flicker   +3 more
wiley   +1 more source

Clinical Efficacy and Safety of Topical Roflumilast in Psoriasis: An Updated Systematic Review and Meta‐Analysis of Randomized Controlled Trials

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Traditional first‐line topical treatments for plaque psoriasis, particularly corticosteroids and vitamin D analogs, frequently have only limited efficacy for long‐term use, and present difficulties with safety and adherence. Objectives In this systematic review and meta‐analysis of randomized controlled trials (RCTs), we assessed ...
Aimal A. Khattak   +11 more
wiley   +1 more source

Alterations in MicroRNA and Cytokine Expressions in Placental and Amniotic Tissues of COVID‐19 Affected Pregnant Women

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Since 2019, coronavirus disease 2019 (COVID‐19) has been associated with increased risks of preterm birth and placental complications. We prospectively investigated alterations in microRNAs (miRNAs) and cytokines in placental and amniotic tissues from pregnant women with and without COVID‐19 to evaluate the infection's impact on pregnancy ...
Wei‐Chun Chen   +3 more
wiley   +1 more source

The Histidine 382 Residue Influences the Thermal Stability and Binding Propensity of the E2 Domain of Amyloid Precursor Protein

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The E2 domain of amyloid precursor protein (APP_E2) plays a central role in the protein's function. We reinvestigate how the missense mutation, ΔH382L, affects the domain's thermal stability and ligand binding propensity through differential scanning fluorometry.
Sphamandla Ndlovu   +4 more
wiley   +1 more source

Sustainable Business Models and Environmental Innovation Capacity: The Moderating Role of Board Effectiveness

open access: yesSustainable Development, EarlyView.
ABSTRACT Sustainable Business Models (SBMs) reflect the degree to which sustainability principles are embedded across firms' business model architectures. However, the mere adoption of these models does not guarantee improvements in environmental innovation capacity due to internal organizational inertia.
Emma García‐Meca   +2 more
wiley   +1 more source

Surface Engineering of Ti3C2Tx MXenes via Silanol Functionalization for Improved Electrochemical Performance

open access: yesSmall, EarlyView.
This study explores the covalent functionalization of Ti3C2Tx using 5,5′‐bis(triisopropoxysilyl)‐2,2′‐bipyridine in different solvents, revealing that only m‐xylene enables effective covalent bonding, ensuring structural stability and preventing layer swelling.
Abelardo Sánchez‐Oliva   +11 more
wiley   +1 more source

Self‐Organized Vascularized Human Liver Spheroids: Serum‐Free Culture Conditions and Use as Tissue Building Blocks

open access: yesSmall, EarlyView.
This approach addresses a major challenge in tissue engineering: creating larger, vascularized tissues. Microvascular networks in liver spheroids are developed through self‐organization mediated by mesenchymal stem cells. These spheroids are maintained in serum‐reduced or serum‐free medium and serve as building blocks to form planar tissue layers ...
Alina Filatova   +10 more
wiley   +1 more source

Theranostic π Electron‐Stabilized Polymeric Micelles for PET Imaging‐Guided Drug Delivery to Tumors

open access: yesSmall, EarlyView.
Cancer nanomedicine efficacy is limited by heterogeneous nanoparticle accumulation in tumors. Nuclear imaging offers non‐invasive, patient‐ and lesion‐specific visualization and quantification of nanoparticle uptake. We present a positron emission tomography (PET)‐imageable micelle platform for direct quantification of nanoparticle accumulation and ...
Alec Wang   +21 more
wiley   +1 more source

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