Structural insights into cobalamin loading and reactivation of human methionine synthase [PDF]
Human methionine synthase (MTR) is an essential enzyme of one carbon metabolism. Consisting of a catalytic N-half and a cobalamin binding C-half, MTR utilises this intricate organometallic cofactor in the methyl transfer from methyltetrahydrofolate to ...
Douglas S. M. Ferreira +13 more
doaj +2 more sources
Mismatch-time ratio combined with ASPECTS: a novel indicator of favorable prognosis in multimodal ct prediction of anterior circulation large vessel occlusion [PDF]
Background Patients with acute ischemic stroke from large vessel occlusion (AIS-LVO) require computed tomography(CT) at stroke centers to determine eligibility for endovascular therapy (EVT).However, the performance of prognostic prediction methods using
Yan Huang +13 more
doaj +2 more sources
Calibration of a Single-Cell Calorimeter in a New Transient-state Test Bench [PDF]
The nuclear radiation energy deposition rate is a key value for the thermal design of experiments, on materials and nuclear fuels, carried out in experimental channels of nuclear research reactors.
Burn J. +6 more
doaj +1 more source
Background. Polycystic ovary syndrome (PCOS) is a multifactorial disease in the development of which gene polymorphism plays an important role.
T.L. Arkhypkina +3 more
doaj +1 more source
Interactive effect of multi-tier response and advanced airway management on clinical outcomes after out-of-hospital cardiac arrest: a nationwide population-based observational study [PDF]
Objective We hypothesized that a multi-tier response (MTR) will provide high-quality cardiopulmonary resuscitation including airway management. However, the type of tier response system and airway management will have different interactive effects ...
Hyouk Jae Lim +5 more
doaj +1 more source
Histologically, chronic demyelinating lesions in multiple sclerosis (MS) have been shown to include inactive lesions that do not change over time and active or “smouldering" lesions that tend to enlarge over time and are surrounded by pro-inflammatory ...
M. S. Matrosova +4 more
doaj +1 more source
The Effect of the Makassar Tidak Rantasa (MTR) Policy on Environmental Cleanliness in Makassar City
This study aims to prove the research hypothesis regarding the Effect of Makassar Tidak Rantasa (MTR) Policy on Environmental Cleanliness in Makassar City. Measurement of Environmental Hygiene Variables is Communication, Resources, Bureaucratic Structure
Inrinofita Sari +2 more
doaj +1 more source
Polymorphism of Folate metabolism genes and risk of lung cancer
Lung cancer is the most commonly diagnosed cancer and the leading cause of cancer mortality worldwide. Folate metabolism plays an important role in carcinogenesis through its involvement in the process of dNamethylation and repair.The aim of our study ...
M. L. Bakanova +3 more
doaj +1 more source
Full-Scale Model Test of Subway Contact Channel under Mechanical Construction
The mechanical construction method for a subway contact channel has the advantages of a short construction period and high safety, and is more and more being applied in coastal soft-soil areas. In order to explore the suitability of this method in inland
Liping Fan +6 more
doaj +1 more source
Periventricular magnetisation transfer abnormalities in early multiple sclerosis
Objective: Recent studies suggested that CSF-mediated factors contribute to periventricular (PV) T2-hyperintense lesion formation in multiple sclerosis (MS) and this in turn correlates with cortical damage.
Lukas Pirpamer +9 more
doaj +1 more source

