Results 201 to 210 of about 12,230 (243)

Human IDO2 exhibits unique binding affinities distinct to those of human IDO1

open access: yesThe FEBS Journal, EarlyView.
Although indoleamine 2,3‐dioxygenase 2 (IDO2) is highly homologous to IDO1, it displays markedly lower catalytic activity. We found that IDO2 binds L‐tryptophan (L‐Trp) in a flipped orientation stabilized by the IDO2‐specific residue His143. Replacement of His143 with the IDO1‐equivalent tyrosine restored an IDO1‐like binding mode and increased ...
Shunsuke Nogi   +8 more
wiley   +1 more source

Genetic dissection reveals distinct contributions of the eS31 N‐terminal domain to translational accuracy in Saccharomyces cerevisiae

open access: yesThe FEBS Journal, EarlyView.
The eukaryote‐specific N‐terminal domain (NTD) of eS31 uses two distinct strategies to maintain translation fidelity. During elongation, a positively charged “hotspot” fine‐tunes the selection of incoming aa‐tRNA. During termination, the entire NTD acts as a structural scaffold to ensure the correct positioning of the release factor eRF1.
Qingxuan Gao   +3 more
wiley   +1 more source

An Alien Word? Cosmic Salvation within a Rahnerian Framework

open access: yesThe Heythrop Journal, EarlyView.
Abstract The possibility of life beyond our planet raises serious theological questions for Christians, particularly in the realm of soteriology. How would Jesus of Nazareth relate to such creatures? Is he the ‘universal’ saviour, in the cosmic sense? Or are there other incarnations of the Logos, the Word or Son of God?
Brandon R. Peterson
wiley   +1 more source

Seasonality and plasticity in the use of native and introduced plant resources by a large forest parrot

open access: yesIbis, EarlyView.
Human‐induced environmental change is reshaping plant communities, requiring native animals to adapt their foraging behaviour to track and exploit novel food resources. Trees such as pines (Pinus spp.) introduced for plantation forestry outside of their native ranges often become naturalized.
Tirth Vaishnav   +2 more
wiley   +1 more source

Determinants of pain, anxiety and patient satisfaction during intravenous injection: a cross-sectional study. [PDF]

open access: yesBMJ Open
Yıldız GN   +5 more
europepmc   +1 more source

Fly me to the canopy: Diptera communities in oak forest crowns as bioindicators of stand decline

open access: yesInsect Conservation and Diversity, EarlyView.
Diptera diversity: Oak decline increases the overall Diptera diversity, particularly in saproxylic and floricolous guilds, likely due to more open canopies and greater deadwood and floral resource availability. Family responses: Dolichopodidae, Empididae, Hybotidae and Anthomyiidae thrive in declining stands, whereas Mycetophilidae and other fungus ...
Anastasia Paupe   +32 more
wiley   +1 more source

Home - About - Disclaimer - Privacy