Results 71 to 80 of about 9,914 (221)

Clinical pattern and treatment outcome of cutaneous leishmaniasis patients in Somali region, eastern Ethiopia

Skin Health and Disease
Background Neglected tropical diseases, affecting over a billion people, include leishmaniasis, a protozoan parasite found in over 20 species. It is classified into three types: visceral, cutaneous, and muco‐cutaneous leishmaniasis, with cutaneous ...
Abdilahi Ibrahim Muse, Muse Obsiye Ibrahim, Muse Ahmed Ibrahim   +2 more
doaj   +1 more source

Custo-efetividade de estratégias de prevenção contra a leishmaniose tegumentar americana na Argentina [PDF]

, 2013
The aim of this study was to estimate the cost-effectiveness of reducing tegumentary leishmaniasis transmission using insecticide-impregnated clothing and curtains, and implementing training programs for early diagnosis.
Orellano, Pablo Wenceslao, Salomon, Oscar Daniel, Vazquez, Néstor   +2 more
core   +1 more source

Testing of four Leishmania vaccine candidates in a mouse model of infection with Leishmania (Viannia) braziliensis, the main causative agent of cutaneous leishmaniasis in the new world [PDF]

, 2007
We evaluated whether four recombinant antigens previously used for vaccination against experimental infection with Leishmania (Leishmania) major could also induce protective immunity against a challenge with Leishmania (Viannia) braziliensis, the species
Ba Brazil, C. Brodskyn, C. I. Oliveira, C. L. Barbiéri, G. Salay, M. L. Dorta, M. M. Rodrigues, N. M. Santos, R. A. Mortara   +8 more
core   +3 more sources

Mitochondrial Dysfunction Induced by a Novel Salicylate‐Based 1,2,3‐Triazole Salt With Potent Antileishmanial Activity

Chemical Biology &Drug Design, Volume 106, Issue 6, December 2025.
A novel salicylate‐based 1,2,3‐triazole salt was synthesized and demonstrated potent and selective activity against Leishmania amazonensis. The most active compound induced mitochondrial dysfunction without hemolytic effects. In silico analyses also suggested favorable pharmacokinetic properties and oral bioavailability.
Bruno A. De Oliveira, Ari Sérgio de Oliveira Lemos, João Pedro Reis Costa Bastos, Luciana Maria Ribeiro Antinarelli, Ana Luiza Ribeiro de Freitas, Raissa Guedes Mattosinhos Ribeiro, Adolfo Firmino da Silva Neto, Elaine Soares Coimbra, Adilson David Da Silva   +8 more
wiley   +1 more source

Mapping the Burden of Tegumentary Leishmaniasis in South America: A Systematic Review and Meta‐Analysis

Tropical Medicine &International Health, Volume 30, Issue 12, Page 1261-1268, December 2025.
ABSTRACT Introduction In recent years, the global burden of tegumentary leishmaniasis (TL) has significantly increased in the Americas. Objective To estimate the prevalence of TL in South America based on publications from the past 13 years. Methods Three databases were searched, and articles were selected based on inclusion criteria and methodological
Sérgio Caldas, Job Alves de Souza Filho, Janete Soares Coelho Santos, Felipe Campos de Melo Iani, Cristiane Faria de Oliveira Scarponi   +4 more
wiley   +1 more source

Leishmaniasis: Recent epidemiological studies in the Middle East

Frontiers in Microbiology, 2023
Leishmaniasis, one of the most neglected tropical diseases (NTDs), is the third most important vector-borne disease worldwide. This disease has a global impact and severity of the infection and is greatest in the Middle East.
Chinyere A. Knight, David R. Harris, Shifaa O. Alshammari, Ayele Gugssa, Todd Young, Clarence M. Lee   +5 more
doaj   +1 more source

World Association for Veterinary Dermatology Consensus Statement for Diagnosis, and Evidence‐Based Clinical Practice Guidelines for Treatment and Prevention of Canine Leishmaniosis

Veterinary Dermatology, Volume 36, Issue 6, Page 723-787, December 2025.
Hyperkeratosis of (a) the footpads and (b) the nasal planum. ABSTRACT Background Canine leishmaniosis (CanL) due to Leishmania infantum remains common, and veterinarians do not always follow scientifically sound approaches for diagnosis, treatment and prevention. Objectives To provide consensus guidelines for diagnosis and evidence‐based guidelines for
Manolis N. Saridomichelakis, Gad Baneth, Silvia Colombo, Filipe Dantas‐Torres, Lluís Ferrer, Alessandra Fondati, Guadalupe Miró, Laura Ordeix, Domenico Otranto, Chiara Noli   +9 more
wiley   +1 more source

Natural history of a visceral leishmaniasis outbreak in highland Ethiopia [PDF]

, 2009
In May 2005, visceral leishmaniasis (VL) was recognized for the first time in Libo Kemken, Ethiopia, a highland region where only few cases had been reported before. We analyzed records of VL patients treated from May 25, 2005 to December 13, 2007 by the
Alvar, J, Aparicio, P, Argaw, D, Bashaye, S, Bern, C, Bernal, O, Flevaud, L, Herrero, M, Lima, M A, Mulugeta, A, Orfanos, G, Palma, P P, Parreño, F, Pedraza, J, Rubens, D   +14 more
core   +1 more source

Type I interferons induced by endogenous or exogenous viral infections promote metastasis and relapse of leishmaniasis. [PDF]

, 2017
The presence of the endogenous <i>Leishmania</i> RNA virus 1 (LRV1) replicating stably within some parasite species has been associated with the development of more severe forms of leishmaniasis and relapses after drug treatment in humans ...
Beverley, S.M., Castiglioni, P., Cusi, M.G., Desponds, C., Eren, R.O., Fasel, N., Hartley, M.A., Kuhlmann, F.M., Prével, F., Ronet, C., Rossi, M., Utzschneider, D.T., Zehn, D.   +12 more
core   +1 more source

A Forgotten Foe Returns: The Diagnostic Odyssey of Kala‐Azar Masquerading as Myelodysplastic Syndrome in a Post‐Elimination Era

Clinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT We report a diagnostically complex case of visceral leishmaniasis (Kala‐azar) in a 73‐year‐old male from a country where the disease was eliminated in 2023. The patient presented with a 2‐month history of low‐grade fever, fatigue, progressive skin hyperpigmentation over 2 years, and hepatosplenomegaly.
Sumaya Khan Mifty, Saiful Islam Chowdhury, Tahmidur Rahman, Tanveer Al Razi Khan, Swagota Roy, Faiza Ahmmed, Md. Sabbir Hossain, Ibrahim Khalil   +7 more
wiley   +1 more source