Results 81 to 90 of about 5,563 (197)

Novel Nonsense Mutation in SMARCD2 Gene Results in Dysplasia of All Myeloid Cell Lines

eJHaem, Volume 6, Issue 6, December 2025.
ABSTRACT Introduction Specific granule deficiency type II (SGD2) is a rare heterogeneous congenital disease characterized by early‐onset life‐threatening infections. SGD2 is caused by autosomal recessive mutations in the SMARCD2 gene. Methods Prenatal screening in our patient revealed a novel homozygous nonsense mutation in SMARCD2 (c.208C>T, p.Gln70*).
Michelle A. E. Brouwer, Arie Arensman, H. Rob Taal, Emilie P. Buddingh, Su Ming Sun, Anthon Hulsmann, Lenneke Waals‐Prinzen   +6 more
wiley   +1 more source

Mitochondrial Dysfunction Induced by a Novel Salicylate‐Based 1,2,3‐Triazole Salt With Potent Antileishmanial Activity

Chemical Biology &Drug Design, Volume 106, Issue 6, December 2025.
A novel salicylate‐based 1,2,3‐triazole salt was synthesized and demonstrated potent and selective activity against Leishmania amazonensis. The most active compound induced mitochondrial dysfunction without hemolytic effects. In silico analyses also suggested favorable pharmacokinetic properties and oral bioavailability.
Bruno A. De Oliveira, Ari Sérgio de Oliveira Lemos, João Pedro Reis Costa Bastos, Luciana Maria Ribeiro Antinarelli, Ana Luiza Ribeiro de Freitas, Raissa Guedes Mattosinhos Ribeiro, Adolfo Firmino da Silva Neto, Elaine Soares Coimbra, Adilson David Da Silva   +8 more
wiley   +1 more source

First molecular-based detection of mucocutaneous leishmaniasis caused by Leishmania major in Iran

Journal of Infection in Developing Countries, 2013
Mucocutaneous leishmaniasis, which mostly occurs in the New World, is mainly associated with Leishmania braziliensis and to a lesser degree L. panamensis and L. amazonensis infections.
Abdolvahab Alborzi, Gholam R Pouladfar, Abdolkarim Ghadimi Moghadam, Armin Attar, Nima Drakhshan, Mohsen Khosravi Maharlooei, Mohsen Kalantari   +6 more
doaj   +1 more source

Mapping the Burden of Tegumentary Leishmaniasis in South America: A Systematic Review and Meta‐Analysis

Tropical Medicine &International Health, Volume 30, Issue 12, Page 1261-1268, December 2025.
ABSTRACT Introduction In recent years, the global burden of tegumentary leishmaniasis (TL) has significantly increased in the Americas. Objective To estimate the prevalence of TL in South America based on publications from the past 13 years. Methods Three databases were searched, and articles were selected based on inclusion criteria and methodological
Sérgio Caldas, Job Alves de Souza Filho, Janete Soares Coelho Santos, Felipe Campos de Melo Iani, Cristiane Faria de Oliveira Scarponi   +4 more
wiley   +1 more source

The accuracy of the Montenegro skin test for leishmaniasis in PCR-negative patients

Revista da Sociedade Brasileira de Medicina Tropical, 2020
INTRODUCTION: As highly specific molecular biology-based techniques may not be sensitive enough for the diagnosis of American tegumentary leishmaniasis (ATL), clinicians frequently rely on immunological tests before treatment initiation.
Ana Bárbara Sapienza Pinheiro, Patricia Shu Kurizky, Marina de Freitas Ferreira, Marco Antonio de Souza Mota, Jaqueline Santos Ribeiro, Edson Zuza de Oliveira Filho, Carlos Augusto Souza, Daniel Holanda Barroso, Raimunda Nonata Ribeiro Sampaio, Ciro Martins Gomes   +9 more
doaj   +1 more source

Cerebral Complication of Cutaneous Leishmaniasis: about a case

Journal de la Faculté de Médecine d'Oran, 2022
Leishmaniasis (L) is a cutaneous, mucocutaneous, or visceral disease caused by intracellular Leishmania protozoan parasites that are transmitted by the bite of female sand flies.
Schahrazed Linda MAGUENOUCHE, Radia BENALIA, Samira Makri MOKRANE   +2 more
doaj  

Dermatologic and otorhinolaryngologic manifestations in leishmaniasis

International Archives of Otorhinolaryngology, 2011
Introduction: Leishmaniasis is an extremely important parasitic disease as regards epidemiology, and, in such a disease, man is an occasional host to the Leishmania protozoon.
Mota, Luiz Alberto Alves, Miranda, Roberta Ribeiro   +1 more
doaj  

Leishmaniasis in humans and small animals: Updates and insights through a one health

Letters in Animal Biology
Leishmaniasis is neglected infectious disease caused by a type of microscopic parasite called Leishmania spp. This disease can affect both humans and animals, as well as sandflies.
Amirhossein Badkoubi , Niloofar Sanaeiha, Narges Safari, Zahra Dolati, Amirreza Khodakarami, Rastin Safari, Mohammad Arad Zandieh   +6 more
doaj   +1 more source

Experimental canine mucocutaneous leishmaniasis (Leishmania braziliensis braziliensis) [PDF]

, 1988
Claude Pirmez, M. C. A. Marzochi, S. G. Coutinho   +2 more
openalex   +1 more source

Coexistence of Recidivans, Mucocutaneous and Osseous Leishmaniasis in an Immunocompromised Patient

, 2022
Hira Tariq, Shahbaz Aman, Ambereen Anwar, Ameena Ashraf   +3 more
openalex   +2 more sources