Results 1 to 10 of about 21,835 (136)

Fatal Outcome of Membranoproliferative Glomerulonephritis in a Patient With Hidden Visceral Leishmaniasis. [PDF]

Case Rep Infect Dis
Background: Visceral leishmaniasis (VL) is a systemic parasitic disease with diverse clinical manifestations, primarily affecting the spleen, liver, and bone marrow. While renal involvement in VL is well documented, it is often mild and resolves with effective treatment.
Mansoursamaei A, Valikhani M, Rafiee H.
europepmc   +2 more sources

Clinical periodontal diagnosis

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi, Andrea Roccuzzo, Jean‐Claude Imber, Alexandra Stähli, Björn Klinge, Niklaus P. Lang   +5 more
wiley   +1 more source

Rituximab for the Management of an Australian Cohort of Treatment Refractory Mucous Membrane Pemphigoid

Australasian Journal of Dermatology, EarlyView.
ABSTRACT Background Mucous membrane pemphigoid (MMP) has a broad range of clinical manifestations, from relatively benign self‐limiting oral lesions to significant scarring (cicatrizing) of the oral, nasal and ocular tissues with severe functional impairment and morbidity.
Bronte Jeffrey, Mark Schifter, Elizabeth Arena, Emily Sullivan, Stephanie Rose, David Joo, David Campbell, Suzanne Culican, David McDonald, Ming Wei Lin   +9 more
wiley   +1 more source

The Spectrum of Epidermolysis Bullosa in KwaZulu‐Natal, South Africa

International Journal of Dermatology, EarlyView.
ABSTRACT Background Epidermolysis bullosa (EB) is a rare, heterogeneous genodermatosis characterized by skin fragility due to inherited defects in genes encoding proteins that maintain epidermal–dermal integrity. The severity and complications of EB vary by subtype, and no cure currently exists. The epidemiology is unknown in South Africa. Methods This
Antoinette Chateau, Thirona Naicker, Cassandra Bruce‐Brand, Johann Schneider, Colleen Aldous, Ncoza Dlova, Hui‐Ching Cheng, Pei‐Chi Lin, Hsin‐Yu Huang, Chao‐Kai Hsu, John A. McGrath   +10 more
wiley   +1 more source

Impact of Topical Fluocinonide on Oral Lichen Planus Evolution: Randomized Controlled Clinical Trial

Oral Diseases, Volume 31, Issue 2, Page 510-521, February 2025.
ABSTRACT Objective To examine the impact of fluocinonide 0.05% gel formulation for the topical treatment of oral lichen planus (OLP). Methods Through an RCT design, 47 patients with OLP were randomly allocated for topical OLP treatment with fluocinonide 0.05% (n = 23) or placebo (n = 24). Patients were examined for OLP symptoms, signs, disease severity,
Alessandro Polizzi, Gianluca Martino Tartaglia, Simona Santonocito, Angela Alibrandi, Anna Elisa Verzì, Gaetano Isola   +5 more
wiley   +1 more source

Integration of Machine Learning‐QSAR and Polypharmacology in Drug Discovery for Leishmaniasis Using Natural and Repurposed Compounds

ChemistrySelect, Volume 10, Issue 21, June 4, 2025.
Leishmaniasis affects over 1 billion people worldwide, with current treatments limited by toxicity and efficacy. This study used machine learning (ML), QSAR, and polypharmacology to identify potential drug candidates, analyzing 12,072 compounds with random forest and XGBoost models.
Laís Salvador do Amaral, Amiel Artur Morais, Alexandre de Fátima Cobre, Raul Edison Luna Lazo, Dile Pontarolo Stremel, Jaqueline Carneiro, Luana Mota Ferreira, Roberto Pontarolo   +7 more
wiley   +1 more source

Hughes–Stovin Syndrome: A Rare Cause of Pulmonary Artery Aneurysm and Thrombosis—A Case Report

International Journal of Rheumatic Diseases, Volume 28, Issue 4, April 2025.
ABSTRACT Hughes–Stovin Syndrome (HSS) is a rare, life‐threatening condition characterized by thrombophlebitis and pulmonary artery aneurysms, often viewed as a variant of Behçet's disease. Its diagnosis and management are challenging due to its rarity and overlapping symptoms with other vascular disorders.
Abdul Qadir, Amal Wael Abdellatif, Aamir Waheed, Mamunul Islam   +3 more
wiley   +1 more source

Advances in cervical cancer: current insights and future directions

Cancer Communications, Volume 45, Issue 2, Page 77-109, February 2025.
Abstract In alignment with the World Health Organization's strategy to eliminate cervical cancer, substantial progress has been made in the treatment of this malignancy. Cervical cancer, largely driven by human papillomavirus (HPV) infection, is considered preventable and manageable because of its well‐established etiology.
Miaochun Xu, Canhui Cao, Peng Wu, Xiaoyuan Huang, Ding Ma   +4 more
wiley   +1 more source

Course of immune thrombocytopenia according to the site of platelet destruction identified by indium‐111 platelet scintigraphy

British Journal of Haematology, Volume 206, Issue 1, Page 279-289, January 2025.
In primary immune thrombocytopenia (ITP), predictors of disease evolution and treatment response are needed. Data based on the site of platelet destruction are scarce, yet Indium‐111 platelet scintigraphy (IPS) could be helpful to help physicians in choosing specific treatments.
Pauline Durand, Valérie Pottier, Frédéric Debordeaux, Charles Mesguich, Pierre Duffau, Estibaliz Lazaro, Jean‐François Viallard, Etienne Rivière   +7 more
wiley   +1 more source

Dedicated diagnostic approaches for mature B‐cell non‐Hodgkin lymphomas occurring in children, adolescents, and young adults

Histopathology, Volume 86, Issue 1, Page 17-37, January 2025.
Age‐specific biologic features on B‐cell non‐Hodgkin lymphoma. Non‐Hodgkin lymphoma (NHL) represents the fourth most common malignant disease among children and adolescents. Current disease classifications, including the most recent World Health Organization (WHO) classification and the International Consensus Classification (ICC), rely on a ...
Ana C Xavier, Andishe Attarbaschi, Dita Gratzinger, Olga Balagué   +3 more
wiley   +1 more source