Results 31 to 40 of about 2,806 (115)

Pyloric atresia-junctional epidermolysis bullosa syndrome showing novel c.4505-4508insACTC mutations in integrin b4 gene (ITGB4)

The Turkish Journal of Pediatrics, 2015
Epidermolysis bullosa (EB) is a group of inherited blistering skin diseases that vary widely in their pathogenesis and severity. It has been divided into distinct subtypes depending on the level of tissue separation in the dermal- epidermal ...
Mehmet Mutlu, Ersan Kalay, Beril Dilber, Yakup Aslan, Embiya Dilber, Nour Almaani, John A Mcgrath   +6 more
doaj  

Unveiling the Leishmanicidal Mechanism of 4‐Nerolidylcatechol Isolated From Piper peltatum Against Leishmania infantum

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT The present study assessed the leishmanicidal activity of 4‐nerolidylcatechol (4‐NC) (1) isolated from Piper peltatum leaves against promastigotes and amastigotes of Leishmania amazonensis, L. braziliensis, and L. infantum. The plant was fractionated, leading to the isolation and chemical identification of 4‐NC (1). Biochemical techniques were
Fabiana Brusco Lorenzetti, Rodolfo Bento Balbinot, Danielle Lazarin‐Bidóia, Viviane dos Santos Faiões, Eduardo Caio Torres‐Santos, Celso Vataru Nakamura, Tânia Ueda‐Nakamura, Diógenes Aparício Garcia Cortez, Benedito Prado Dias Filho   +8 more
wiley   +1 more source

Clinicopathologic features of Lichen planus patients in Mashhad-Iran

مجله دانشگاه علوم پزشکی گرگان, 2010
Background and Objective: Lichen planus presents with chronic, inflammatory mucocutaneous lesions with almost 1-2% prevalency without any relation to demographic variables. This study was done to describe the clinical pathologic features of lichen planus
Mashayekhi Ghoyonlo V (MD), Tayebi Mabody N (MD), Safaie B (MD), Ebrahimirad M (MD), Haghani A (MD)   +4 more
doaj  

Genetic risk factors and clinical manifestations of systemic lupus erythematosus: Large‐scale analysis of genetic predisposition and disease subtypes

Journal of Internal Medicine, Volume 299, Issue 1, Page 95-108, January 2026.
Abstract Background Systemic lupus erythematosus (SLE) is an autoimmune disease with a heterogenous clinical picture. This study aimed to link genetic SLE predisposition with relevant clinical manifestations. Method Datasets best corresponding to the 11 American College of Rheumatology 1982 (ACR‐82) classification criteria for SLE in a large, public ...
Sarah Reid, Johanna K. Sandling, Pascal Pucholt, Ahmed Sayadi, Martina Frodlund, Karoline Lerang, Iva Gunnarsson, Andreas Jönsen, Ann‐Christine Syvänen, Øyvind Molberg, Solbritt Rantapää‐Dahlqvist, Anna Rudin, Christopher Sjöwall, Elisabet Svenungsson, Anders A. Bengtsson, Lars Rönnblom, Dag Leonard   +16 more
wiley   +1 more source

JAK Inhibitors as a Novel Approach to Autoimmune Bullous Diseases: A Review

Dermatologic Therapy, Volume 2026, Issue 1, 2026.
Autoimmune bullous diseases (AIBDs) are a group of chronic disorders characterized by blister formation resulting from abnormal immune responses. Janus kinase (JAK) inhibitors have emerged as promising therapeutic agents for AIBDs. This review discusses the use of JAK inhibitors—such as upadacitinib, baricitinib, tofacitinib, and abrocitinib, among ...
Olga Olisova, Yuliya Kolesova, Natalia Teplyuk, Ekaterina Grekova, Leyi Ni, Alina Mardanova, Karim Karray, Anastasiia Tikhonova, Anfisa Lepekhova, Jaime Piquero-Casals   +9 more
wiley   +1 more source

Cutaneous Marginal Zone Lymphoproliferation Arising from Circumorificial Plasmacytosis During Nivolumab Therapy for Urothelial Carcinoma

Dermato
Immune checkpoint inhibitors (ICIs), particularly PD-1/PD-L1 antibodies, have significantly improved outcomes in a variety of solid tumors, including urothelial carcinoma.
Thilo Gambichler, Heinz-Wolfram Bernd, Sera Weyer-Fahlbusch, Anke Lücke, Johann Lorenzen, Laura Susok   +5 more
doaj   +1 more source

Application of Local Hyperthermia Therapy Based on Immune Cell Function in Cutaneous Infectious Diseases

Dermatologic Therapy, Volume 2026, Issue 1, 2026.
Hyperthermia represents a physiological state marked by an elevation in body temperature due to the malfunctioning of thermoregulatory mechanisms. It transpires when the body either generates or absorbs a greater amount of heat than it is capable of expelling.
Zhiya Yang, Li Zhao, Yonghong Zhang, Dongmei Li, Dongmei Shi, Suraiya Saleem   +5 more
wiley   +1 more source

Oxidative Stress Modulation and Antileishmanial Activity of Salvinia auriculata

Chemistry &Biodiversity, Volume 22, Issue 12, December 2025.
Ethanolic extract of Salvinia auriculata showed significant antioxidant and antileishmanial activities. Salviniside II, the major metabolite, was isolated, structurally characterized, and evaluated, but exhibited weaker antiparasitic effects when compared to the whole extract.
Augusto César Rodrigues, Emilha Uzum Papaya, Fernanda da Silva, Carla Cardozo Pinto de Arruda, Edson Lucas dos Santos, Kely de Picoli Souza, Carlos Alexandre Carollo   +6 more
wiley   +1 more source

Acquired Haemophilia Occurring in Association With Bullous Pemphigoid

JEADV Clinical Practice, Volume 4, Issue 5, Page 1196-1201, December 2025.
Capsule summary This case series of seven elderly patients describes the rare association between bullous pemphigoid (BP) and acquired haemophilia A (AHA). AHA typically developed within six months of BP onset, often coinciding with disease flares, and presented with distinctive bleeding manifestations such as haemorrhagic bullae and gastrointestinal ...
Wen Yang Benjamin Ho, Zi Teng Chai, Haur Yueh Lee, Yen Loo Lim   +3 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: G protein‐coupled receptors

British Journal of Pharmacology, Volume 182, Issue S1, Page S24-S151, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Anthony P. Davenport, Eamonn Kelly, Alasdair J. Gibb, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Maria Pia Abbracchio, George R. Abraham, Alexander Agoulnik, Wayne Alexander, Khaled Al‐hosaini, Magnus Bäck, Jillian G. Baker, Nicholas M. Barnes, Ross Bathgate, Jean‐Martin Beaulieu, Annette G. Beck‐Sickinger, Maik Behrens, Kirstie A. Bennett, Kenneth E. Bernstein, Bernhard Bettler, Nigel J. M. Birdsall, Victoria A. Blaho, Pascal Bonaventure, Francois Boulay, Corinne Bousquet, Hans Bräuner‐Osborne, Andrew J. Brown, Geoffrey Burnstock, Marta Busnelli, Girolamo Caló, Vanni Caruso, Justo P. Castaño, Kevin J. Catt, Stefania Ceruti, Paul Chazot, Nan Chiang, Bice Chini, Arthur Christopoulos, Jerold Chun, Antonia Cianciulli, Olivier Civelli, Lucie H. Clapp, Réjean Couture, Helen M. Cox, Zsolt Csaba, Claes Dahlgren, Frank M. Dautzenberg, Gordon Dent, Steven D. Douglas, Pascal Dournaud, Margarita L. Dubocovich, Satoru Eguchi, Emanuel Escher, Edward J. Filardo, Tung Fong, Huamei Fu Forsman, Marta Fumagalli, Raul R. Gainetdinov, Michael L. Garelja, Marc de Gasparo, Florence Gbahou, Craig Gerard, Marvin Gershengorn, Michelle Glass, David E. Gloriam, Fernand Gobeil, Theodore L. Goodfriend, Cyril Goudet, Lukas Grätz, Karen J. Gregory, Christian Gruber, Andrew L. Gundlach, Jörg Hamann, Julien Hanson, Deborah S. Hartman, Richard L. Hauger, Debbie L. Hay, Akos Heinemann, Laura Heitman, Deron R. Herr, Morley D. Hollenberg, Nicholas D. Holliday, Birgitte Holst, Mastgugu Horiuchi, Daniel Hoyer, László Hunyady, Ahsan Husain, Adriaan P. IJzerman, Tadashi Inagami, Paul A. Insel, Kenneth A. Jacobson, Laura H. Jacobson, Robert T. Jensen, Ralf Jockers, Deepa Jonnalagadda, Sadashiva Karnik, Klemens Kaupmann, Jacqueline Kemp, Charles Kennedy, Yasuyuki Kihara, Julia Kinsolving, Takio Kitazawa, Pawel Kozielewicz, Hans‐Jürgen Kreienkamp, Jyrki P. Kukkonen, Luxmichan Laishram, Tobias Langenhan, Christopher J. Langmead, Dan Larhammar, Katie Leach, Davide Lecca, John D. Lee, Susan E. Leeman, Jérôme Leprince, Rob Leurs, Xaria X. Li, Ines Liebscher, Stephen J. Lolait, Amelie Lupp, Robyn Macrae, Janet J. Maguire, Davide Malfacini, Maurice Manning, Davide Marangon, Kirill Martemyanov, Jean Mazella, Craig A. McArdle, Shlomo Melmed, Martin C. Michel, Laurence J. Miller, Vincenzo Mitolo, Bernard Mouillac, Christa E. Müller, Philip M. Murphy, Jean‐Louis Nahon, Richard R. Neubig, Tony Ngo, Xavier Norel, Duuamene Nyimanu, Anne‐Marie O’Carroll, Stefan Offermanns, Maria Antonietta Panaro, Marc Parmentier, Nicole Perry‐Hauser, Roger G. Pertwee, Jean‐Philippe Pin, Eric R. Prossnitz, Helena Chengxue Qin, Mark Quinn, Stefano Raffaele, Rithwik Ramachandran, Manisha Ray, Rainer K. Reinscheid, Alejandro Romeral Buzón, Philippe Rondard, Mette M. Rosenkilde, G. Enrico Rovati, Chiara Ruzza, Gareth J. Sanger, Nicole Scholz, Torsten Schöneberg, Gunnar Schulte, Stefan Schulz, Deborah L. Segaloff, Charles N. Serhan, Arun K. Shukla, Khuraijam Dhanachandra Singh, Craig M. Smith, Nicola J. Smith, Claudia Stäubert, Leigh A. Stoddart, Yukihiko Sugimoto, Roger Summers, Valerie P. Tan, David M. Thal, Walter ( Wally) Thomas, Pieter B. M. W. M. Timmermans, Kalyan Tirupula, Lawrence Toll, Giovanni Tulipano, Hamiyet Unal, Thomas Unger, Celine Valant, Patrick Vanderheyden, David Vaudry, Hubert Vaudry, Joseph G. Verbalis, Jean‐Pierre Vilardaga, Christopher S. Walker, Ji Ming Wang, Donald T. Ward, Hans‐Jürgen Wester, Gary B. Willars, Tom Lloyd Williams, Trent M. Woodruff, Huixian Wu, Cheng Yang, Chengcan Yao, Richard D. Ye, Nathan Zaidman   +206 more
wiley   +1 more source