Results 41 to 50 of about 1,295,731 (116)

Management of Clinically Node‐Negative Salivary Gland Cancer: Observation, Neck Dissection, or Neck Irradiation?

Head &Neck, Volume 47, Issue 6, Page 1612-1620, June 2025.
ABSTRACT Introduction Salivary gland malignancies are heterogeneous tumors with highly variable outcomes. Elective neck management options include observation, neck dissection (ND), and neck irradiation (NI). We sought to compare outcomes of cN0 salivary gland cancer by elective neck management.
Evelyn O. Ilori, Neil M. Woody, Bryan B. Hair, Lisa Rybicki, Eric D. Lamarre, Jamie Ahn Ku, Brandon Prendes, Joseph Scharpf, Brian B. Burkey, Shlomo A. Koyfman, Shauna R. Campbell   +10 more
wiley   +1 more source

Ablation of Cancer Stem Cells by Therapeutic Inhibition of the MDM2–p53 Interaction in Mucoepidermoid Carcinoma

Clinical Cancer Research, 2018
Purpose: Unique cells characterized by multipotency, self-renewal, and high tumorigenic potential have been recently discovered in mucoepidermoid carcinomas.
A. Andrews, K. Warner, C. Rodriguez-Ramirez, A. Pearson, Felipe Nör, Zhaocheng Zhang, S. Kerk, A. Kulkarni, J. Helman, J. Brenner, M. Wicha, Shaomeng Wang, J. Nör   +12 more
semanticscholar   +1 more source

Diagnosis and Treatment of Primary Tracheobronchial Tumors

Cancer Medicine, Volume 14, Issue 9, May 2025.
ABSTRACT Background Primary tracheobronchial tumors (PTBTs) are rare but life‐threatening, accounting for approximately 0.2% of all respiratory neoplasms. Owing to their nonspecific clinical symptoms, PTBTs are often initially misdiagnosed as bronchial asthma or bronchitis in the early stages.
Chen Shu, Yu‐jian Liu, Kai‐fu Zheng, Xi‐yang Tang, Meng‐chao Li, Yang Shen, Yu‐long Zhou, Wei‐guang Du, Nan Ma, Jin‐bo Zhao   +9 more
wiley   +1 more source

Mucoepidermoid Carcinoma of Arising from a Bronchogenic Cyst of the Diaphragm

Annals of Thoracic and Cardiovascular Surgery, 2018
Introduction: Bronchogenic cysts may rupture or become infected, and malignant degeneration may occur. Although various types of malignant degeneration have been described, only a few reports of mucoepidermoid carcinoma arising from a bronchogenic cyst ...
N. Taira, H. Kawasaki, E. Atsumi, T. Ichi, T. Kawabata, M. Saio, N. Yoshimi   +6 more
semanticscholar   +1 more source

Utility of Proliferation Markers Ki‐67 and PHH3 in Predicting Malignancy in Basaloid Salivary Gland Neoplasms: A Study Using Digital Image Analysis of Cytology Cell Blocks

Diagnostic Cytopathology, Volume 53, Issue 5, Page 238-245, May 2025.
ABSTRACT Introduction Basaloid salivary gland neoplasms (BSNs) are notoriously difficult to classify in fine needle aspiration (FNA) specimens due to the morphologic overlap of benign and malignant entities. Adenoid cystic carcinoma (AdCC) represents a particular diagnostic challenge, as it typically shows low‐grade cytologic features despite its ...
Yanki Yarman, Robert Post, Zachary Breslin, Charalambos C. Solomides, Stacey M. Gargano   +4 more
wiley   +1 more source

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2021–2022

Mass Spectrometry Reviews, Volume 44, Issue 3, Page 213-453, May/June 2025.
Abstract The use of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this review is the 12th update of the original article published in 1999 and brings coverage of the literature to the end of 2022.
David J. Harvey
wiley   +1 more source

Inhibition of Protein Phosphatase 2A Sensitizes Mucoepidermoid Carcinoma to Chemotherapy via the PI3K-AKT Pathway in Response to Insulin Stimulus

Cellular Physiology and Biochemistry, 2018
Background/Aims: Protein phosphatase 2A (PP2A) is a ubiquitous serine/threonine phosphatase that mediates cell cycle regulation and metabolism. Mounting evidence has indicated that PP2A inhibition exhibits considerable anticancer potency in multiple ...
Limin Liu, Herui Wang, Jing Cui, Qi Zhang, Wei Zhang, Wanlin Xu, Hao Lu, Shengwen Liu, Shukun Shen, Francia Fang, Lei Li, Wenjun Yang, Z. Zhuang, Jiang Li   +13 more
semanticscholar   +1 more source

Phase II Study of Nivolumab and Ipilimumab for Treatment of Metastatic/Recurrent Adenoid Cystic Carcinoma (ACC) of all Anatomic Sites of Origin and Other Malignant Salivary Gland Tumors

Cancer Medicine, Volume 14, Issue 7, April 2025.
In patients with recurrent or metastatic adenoid cystic carcinoma (ACC) combination nivolumab with ipilimumab resulted in moderate disease control. Patients with non‐ACC salivary gland carcinomas did not see responses to treatment. ABSTRACT Objective Dual checkpoint inhibitor therapy with nivolumab and ipilimumab has been FDA approved for a number of ...
Young Kwang Chae, Richard Duan, Liam Il‐Young Chung, Youjin Oh, Borislav Alexiev, Sangwon Shin, Sukjun Kim, Irene Helenowski, Maria Matsangou, Victoria Villaflor, Devalingam Mahalingam   +10 more
wiley   +1 more source

An unusual case of intraosseous mucoepidermoid carcinoma of the mandible

Medicine, 2018
Rationale: Mucoepidermoid carcinoma (MEC) is the most common primary salivary gland malignancy. Ectopic MEC can occur in any part of the body, however, only 2% to 4% of MEC could be detected in the jaw, which is named intraosseous mucoepidermoid ...
Xiang Li, Feng Wang, Yufan Wang, Shuai Sun, Hongyu Yang   +4 more
semanticscholar   +1 more source

Polymorphous Adenocarcinoma of the Parotid Gland: A Rare Entity in Asians With a Unique Cystic Presentation

Clinical Case Reports, Volume 13, Issue 4, April 2025.
ABSTRACT Polymorphous adenocarcinoma (PAC) of the parotid is a rare entity with minimal reported incidences in the Asian population. It generally presents as a solid tumor and is considered a diagnostic dilemma due to morphological diversity and variable histological patterns.
Ibadat Preet Kaur, Devendra Pankaj, Meena Santosh, Jitendra Sharan, Neha Singh, Anand Marya   +5 more
wiley   +1 more source