Results 71 to 80 of about 22,611 (251)

Efficacy of Almonertinib Versus Osimertinib as the First‐Line Treatment for Non‐Small Cell Lung Cancer With EGFR L858R Mutation and Prognostic Analysis: A Retrospective Comparative Cohort Study

Cancer Medicine, Volume 14, Issue 23, December 2025.
ABSTRACT Objectives Epidermal growth factor receptor (EGFR)–specific tyrosine kinase inhibitors show less efficacy against the EGFR L858R mutation than EGFR 19del, but no current head‐to‐head clinical trials have been performed comparing the efficacy of almonertinib and osimertinib.
Xiujing Yao, Ruyue Li, Xue Dong, Ying Li, Yintao Li   +4 more
wiley   +1 more source

Dez anos de acompanhamento de uma série de casos de neoplasias epiteliais primárias da glândula lacrimal: características clínicas, tratamento cirúrgico e achados histopatológicos [PDF]

, 2010
PURPOSE: To describe and analyze the features of a cases series of patients with primary epithelial neoplasms of the lacrimal gland, its surgical treatment, and histopathological findings.
Cursino, Sylvia Regina T., Damasceno, Renato Wendell Ferreira [UNIFESP], Dantas, Paulo Elias Correa, De Pontes, Fernanda Silva Lopes, Nishiwaki-dantas, Maria Cristina, Santos, Rodrigo Ribeiro, Vital Filho, José   +6 more
core   +3 more sources

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, Volume 19, Issue 11, Page 3205-3222, November 2025.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Primary intraosseous carcinoma of mandible: an update on review of literature with a case report [PDF]

, 2010
Primary intraosseous carcinoma (PIOC) is a rare malignant neoplasm of the jaws which is locally aggressive with quite poor prognosis. Overall and disease free survival is poor with almost 50% patients failing within first 2 years of follow up and ...
Jindal, Sanjeev Kumar, Puri, Nidhi, Shambhulingappa, P., Sheikh, Soheyl   +3 more
core   +1 more source

Fine needle aspiration cytology of low-grade mucoepidermoid carcinoma of the parotid gland: A diagnostic challenge

Journal of Cytology, 2008
Of the salivary gland tumors, mucoepidermoid carcinoma is probably the most difficult to diagnose accurately by aspiration cytology. It is the second most common tumor in the pediatric age group in parotid gland after pleomorphic adenoma and ...
Rupani Asha, Kavishwar Vikas, Achinmane Vynkatesh, Puranik Gururaj   +3 more
doaj  

Pan‐cyclin‐dependent kinase inhibition is a potential treatment for adenoid cystic carcinoma that downregulates the MYB::NFIB fusion and induces tumor regression

Cancer Communications, EarlyView.
Junchi Huang, Peter Larsson, Maryam Kakay Afshari, Paloma Tejera Nevado, Tajana Tešan Tomić, André Fehr, Fredrik Jäwert, Göran Stenman, Mattias K. Andersson   +8 more
wiley   +1 more source

Primary Sweat Gland Adenocarcinoma of the Skin With ATL2::PRKD3 Fusion: A Potential Cutaneous Analog of Cribriform Adenocarcinoma of the Salivary Glands?

Genes, Chromosomes and Cancer, Volume 64, Issue 11, November 2025.
ABSTRACT Many cutaneous adnexal tumors share molecular alterations with other homologous neoplasms occurring in salivary glands. Polymorphous adenocarcinoma (PAC) is a rare salivary gland tumor, usually associated with alterations in the PRKD gene family.
Anaïs Brunet, Barouyr Baroudjian, Maxence Mancini, Fanélie Jouenne, Baptiste Louveau, Isabelle Moulonguet, Amélie Osio, Samia Mourah, Maxime Battistella   +8 more
wiley   +1 more source

About a rare tumor of the upper lip: the mucoepidermoid carcinoma

The Pan African Medical Journal, 2015
Mucoepidermoid carcinoma represents about 5% of all salivary gland tumors, in which, about one-third occurs in the minor salivary gland. Mucoepidermoid carcinoma is the third most frequently encountered minor salivary gland tumor, preceded only by a ...
Mohamed Mliha Touati, ohammed Lakouichmi
doaj   +1 more source

Temporal‐Parotid Resection for Malignant Parotid Tumors: A Systematic Review

The Laryngoscope, Volume 135, Issue 11, Page 4009-4019, November 2025.
Parotid gland tumors represent a complex surgical challenge. Temporal‐parotid resection (TPR) is indicated to manage temporal bone invasion. Thirteen studies investigated the role of TPR in literature, including 336 patients. High rates of negative margins and local disease control are achieved with TPR.
Antonio Daloiso, Diego Cazzador, Giulia Tealdo, Gioia Martini, Leonardo Franz, Antonio Mazzoni, Piero Nicolai, Elisabetta Zanoletti   +7 more
wiley   +1 more source

Evaluation of p27 Expression in Salivary Gland Neoplasms; A Step Forward in Unveiling the Role of p27 [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: Salivary gland neoplasms are not uncommon lesions that are seen in the head and neck region. The role of cell cycle regulators as well as that of oncogenes remains unexplored in the pathogenesis of these neoplasms.
Nikhil I. Malgaonkar, Abdulwahab Abuderman, MY Kharma, SA Al-Maweri, NA. Alaizari, MA. Altamimi, S. Darwish, Bassel Tarakji   +7 more
doaj   +1 more source