Results 151 to 160 of about 123,311 (332)

Heterogeneity of Intratumoral Microbiota Within the Tumor Microenvironment and Relationship to Tumor Development

Med Research, EarlyView.
Mutual shaping of tumor microbiota and TME. Intratumoral microbiota—comprising diverse bacteria, fungi, viruses, and intracellular organisms—play critical and dynamic roles in shaping the tumor microenvironment (TME). Their spatial and compositional diversity contributes to both intratumoral and intertumoral heterogeneity, influencing immune modulation
Zhifei Gao, Aimin Jiang, Zizhuo Li, Lingxuan Zhu, Weiming Mou, Weitao Shen, Peng Luo, Bufu Tang, Jian Zhang, Anqi Lin   +9 more
wiley   +1 more source

Breaking Boundaries: Chronic Diseases and the Frontiers of Immune Microenvironments

Med Research, EarlyView.
ABSTRACT The immune microenvironment includes immune cells, cytokines, extracellular matrix, vesicles, etc. The interactions between these components form a unique local immune microecology. Although immunity serves as the defense against external pathogens, aberrant immune activation often contributes to disease development.
Guoqing Li, Yuxuan Wan, Alan Jiao, Ke Jiang, Gaoyuan Cui, Jinxin Tang, Simin Yu, Zhengang Hu, Songfeng Zhao, Zhenjie Yi, Lifu Long, Yang Yang, Xuehao Cui, Chunrun Qu   +13 more
wiley   +1 more source

Primary Hepatic Mucosa-Associated Lymphoid Tissue Lymphoma: A Case Report

대한영상의학회지, 2016
Primary hepatic mucosa-associated lymphoid tissue (MALT) lymphoma is an extremely rare lesion. Primary hepatic lymphomas are known to present as a single mass in > 70% of cases, and in many instances with no specific features on imaging.
Kyung Su Kwag, Suk Ki Jang, Jae Woo Yeon, So Ya Paik, Sang Jong Park, Hyuk Jung Kim   +5 more
doaj   +1 more source

Evidence for a Modulatory Effect of a 12‐Week Pomegranate Juice Intervention on the Transcriptional Response in Inflammatory Bowel Disease Patients Reducing Fecal Calprotectin Levels: Findings From a Proof‐of‐Principle Study

Molecular Nutrition &Food Research, EarlyView.
This study investigated how pomegranate juice affects inflammation in patients with inflammatory bowel disease who are currently in remission. After 12 weeks of drinking pomegranate juice, patients showed reduced markers of intestinal inflammation.
Ilaria Minato, Pedro Mena, Luigi Ricciardiello, Eleonora Scaioli, Andrea Belluzzi, Enrica Rotondo, Eleonora Derlindati, Barbara Montanini, Costanza Michelini, Nicole Tosi, Vicente Agullò Garcià, Gianfranco Picone, Carlo Mengucci, Sara Dobani, Paloma Salamanca, Alice Rosi, Margherita Dall'Asta, Letizia Bresciani, Claudio Curti, Enzo Spisni, Alessandra Dei Cas, Alessandra Bordoni, Francisco A. Tomás‐Barberán, Lynnette R. Ferguson, Daniele Del Rio, Francesca Danesi   +25 more
wiley   +1 more source

The role of gut microbiota‐derived metabolites in neuroinflammation

Neuroprotection, EarlyView.
Gut microbiota‐derived metabolites accumulate in the brain, activating or inhibiting microglia and astrocytes, which affects neuroinflammatory progression. The gut microbiota converts the diet into a variety of metabolites, including bile acid, trimethylamine N‑oxide (TMAO), and indole.
Lingjie Mu, Yijie Wang
wiley   +1 more source

Major and Trace Element Composition Differences Revealed in Porcine Intestine by Dynamic Analysis and MeV Ion Microscopy

physica status solidi (a), EarlyView.
Herein, C, N, and Ca concentration images in dry porcine intestine are used to determine trace element concentrations ex vivo. Physiologically relevant concentrations in biological tissue, in the in vivo, state are of the order of μmol L−1 and mmol L−1.
Harry J. Whitlow, Gyula Nagy, Andrej Kuznetsov, Robert J.W. Frost, Alexander Azarov, Karen M. Smith, Sumittra Amphalop, Wimonrut Insuan, Sakulchit Wichianchot, Min‐Quin Ren, Thomas Osipowicz, Chris G. Ryan, Wanwisa Sudprasert, Francois Villinger   +13 more
wiley   +1 more source

Primary pulmonary mucosa-associated lymphoid tissue lymphoma: A case report

Radiology Case Reports, 2022
Primary pulmonary lymphoma (PPL) is a rare entity with the most common presentation as mediastinal lymphadenopathy. The most common form of PPL is Mucosa-Associated Lymphoid Tissue Lymphoma (MALToma) which is an extranodal B-cell lymphoma originating ...
Mohammad Reza Hosseini Siyanaki, MD, Elham Askari, MD, Sara Haseli, MD, Nazanin Sadraei, MD   +3 more
doaj  

Malignancies and immunoglobulin G4‐related disease

Rheumatology &Autoimmunity, EarlyView.
Immunoglobulin G4‐related disease (IgG4‐RD) is associated with increased cancer risk. Malignancies affect both IgG4‐RD involved organs, such as the lung, pancreas, bile duct, and prostate, and noninvolved organs, such as the gastrointestinal duct. B‐cell neoplasms constitute a proportion of the malignancies linked to this disease.
Jingna Li, Wen Zhang
wiley   +1 more source

A randomised phase I study of etrolizumab (rhuMAb β7) in moderate to severe ulcerative colitis. [PDF]

, 2013
ObjectiveEtrolizumab (rhuMAb β7, anti-β7, PRO145223) is a humanised monoclonal antibody targeting the β7 subunit of the heterodimeric integrins α4β7 and αEβ7, which are implicated in leucocyte migration and retention in ulcerative colitis (UC).
Baumgart, Daniel C, Bressler, Brian, Danilenko, Dimitri, Egen, Jackson, Fedorak, Richard N, Hommes, Daan W, Keir, Mary, Luca, Diana, Mansfield, John C, O'Byrne, Sharon, Rutgeerts, Paul J, Schreiber, Stefan, Sturm, Andreas, Tang, Meina, Visich, Jennifer, Wei, Xiaohui, Williams, Marna   +16 more
core  

Potential roles of antibodies with different classes in IgG4‐related diseases

Rheumatology &Autoimmunity, EarlyView.
This review discussed the common characteristics of different classes of antibodies and their potential corresponding unique mechanisms involved in immunoglobulin G4‐related disease. Abstract Immunoglobulin G4‐related disease (IgG4‐RD), first identified two decades ago, is an immune‐mediated pro‐inflammatory and profibrotic disease entity affecting ...
Ling Li, Shaozhe Cai, Shengyan Lin, Lin Bai, Zhihua Yu, Wei Sun, Lingli Dong   +6 more
wiley   +1 more source