British Journal of Pharmacology, EarlyView.Immune checkpoint inhibitors (ICIs) have been a breakthrough in cancer therapy, inducing durable remissions in responding patients. However, they are associated with variable outcomes, spanning from disease hyperprogression to complete responses with the onset of immune‐related adverse events.
Mikhaël Attias, Ciriaco A. Piccirillo
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Gastrointestinal Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma with Synchronous Precancerous/Malignant Epithelial Mucosal Lesions: A Clinico-Pathologic Review [PDF]
, 2022 Sindhuja Sivanandham +2 more
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Stromal Defense Against Cancer: An Unprecedented Mechanism Limiting Cancer Invasion Into the Bone
Cancer Science, EarlyView.The roles of nonimmune systems in tumor regulation remain largely undefined. This article introduces a new concept, “stromal defense against cancer (SDAC),” which is based on recent findings that the periosteum actively responds to tumor proximity and physically impedes tumor invasion into bone.
Masayuki Tsukasaki, Hiroshi Takayanagi
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Preferential Dissemination of B-Cell Gastric Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma to the Splenic Marginal Zone [PDF]
, 1997 Ming‐Qing Du +9 more
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Dupilumab Dampens Mucosal Type 2 Response During Acetylsalicylic Acid Challenge in N‐ERD Patients
Clinical &Experimental Allergy, EarlyView.Dupilumab therapy reduced elevated type 2 cytokine responses post‐ASA provocation in N‐ERD patients, independent of ASA tolerance, and revealed novel mechanistic insights by modulating acute type 2 immunity. Transcriptomic analysis showed concurrent downregulation of lipid and peroxisome pathways during ASA challenge in N‐ERD patients after 24 weeks of
Julia Eckl‐Dorna +10 more
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<i>Helicobacter pylori</i> Reinfection Diagnosed by Endoscopic and Histologic Recurrence in a Patient with Gastric Mucosa-Associated Lymphoid Tissue Lymphoma [PDF]
, 2023 Toshiro Sugiyama +3 more
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Journal of Cutaneous Pathology, EarlyView.ABSTRACT Primary cutaneous aggressive epidermotropic CD8+ cytotoxic T‐cell lymphoma (PCAECTCL) is a rare and aggressive malignancy, with limited documented cases in pediatric patients. This report presents a unique case of a 9‐year‐old female with PCAECTCL, characterized by widespread erythematous annular lesions that exhibited an indolent clinical ...
Carrie Meng +6 more
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Long-term Outcomes of Early-stage Non-stomach Gastrointestinal Mucosa-associated Lymphoid Tissue Lymphoma Treated With Radiation Therapy [PDF]
, 2023 Eiko Ito +6 more
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Emerging Techniques in Minimally Invasive Surgery in Hematologic Malignancies
European Journal of Haematology, EarlyView.ABSTRACT Hematologic malignancies represent the most common cancers in children. While the mainstays of treatment are chemotherapy and potentially hematopoietic stem cell transplant, minimally invasive surgery (MIS) has a role in the diagnosis and management of complications related both to disease and therapy as well as common pediatric surgical ...
Alejandro Chara +3 more
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