Results 191 to 200 of about 123,311 (332)
The role of acquired host immunity in periodontal diseases
Abstract The aim of this narrative review is to relate the contribution of European researchers to the complex topic of the host immune system in periodontal disease, focusing on acquired immunity. Other chapters in this volume will address the genetics and autoantibody responses and other forms of immunity to periodontal disease.
Denis F. Kinane+2 more
wiley +1 more source
Inflammation and mechanical force‐induced bone remodeling
Abstract Periodontitis arises from imbalanced host–microbe interactions, leading to dysbiosis and destructive inflammation. The host's innate and adaptive immune responses produce pro‐inflammatory mediators that stimulate destructive events, which cause loss of alveolar bone and connective tissue attachment.
Hyeran Helen Jeon+6 more
wiley +1 more source
Abstract Acute myeloid leukemia (AML) poses significant challenges in veterinary medicine, with limited treatment options and poor survival rates. While substantial progress has been made in characterizing human AML, translating these advancements to veterinary practice has been hindered by limited molecular understanding and diagnostic tools. The case
R. Adam Harris+5 more
wiley +1 more source
He multiple‐attribute method aids management decisions in in ovo nutrition. In ovo amino acid administration reduces embryo mortality risk late in incubation. In ovo injection of 0.55% L‐tryptophan on day 14 improves broiler growth. In ovo 0.55% L‐tryptophan significantly influenced growth metrics at 21 days.
Marziyeh Ebrahimi+3 more
wiley +1 more source
ILC2 Diversity, Location, and Function in Pulmonary Disease
ABSTRACT Type‐2 inflammation is driven by the production of canonical type‐2 cytokines IL‐4, IL‐5, and IL‐13. Type‐2 cytokines promote mucus production, innate immune cell recruitment, and smooth muscle contractility in mucosal tissues. These hallmarks of type‐2 inflammation are important contributors to the weep‐and‐sweep responses observed in the ...
Mukesh Verma+2 more
wiley +1 more source
ABSTRACT The thymus exhibits constitutive activation of nearly all major inflammatory pathways, including sterile MyD88‐dependent signaling and interferon production by mTECs, the presence of cellular and molecular components of type 1, type 2, and type 3 responses, as well as sustained B cell activation. The reasons for the existence of such a complex
Taras Kreslavsky
wiley +1 more source
Intrathymic Regulation of Dendritic Cell Subsets and Their Contributions to Central Tolerance
ABSTRACT Thymic dendritic cells (DCs) are critical mediators of central tolerance, cooperating with medullary thymic epithelial cells (mTECs) and B cells to establish T‐cell self‐tolerance to the proteome. The DC compartment is highly heterogeneous and is comprised of three major subsets, plasmacytoid dendritic cells (pDCs) and two conventional ...
Aparna Calindi, Lauren I. R. Ehrlich
wiley +1 more source
J. Choi+18 more
semanticscholar +1 more source
ABSTRACT The thymus is a primary lymphoid organ for generating a diverse yet self‐tolerant T cell repertoire. Among the thymic stromal cells that create the thymic microenvironment, thymic epithelial cells (TECs) have received the most attention because of their distinctive functions in the repertoire selection of T cells. Other types of thymic stromal
Ryunosuke Muro, Takeshi Nitta
wiley +1 more source