Results 211 to 220 of about 123,311 (332)

Butyrate alleviates food allergy by improving intestinal barrier integrity through suppressing oxidative stress‐mediated Notch signaling

open access: yesiMeta, Volume 4, Issue 3, June 2025.
Compared to healthy controls, children with food‐sensitized tolerance and food allergy showed reduced fecal short‐chain fatty acids (SCFAs), particularly butyrate. In an ovalbumin‐sensitized mouse model, butyrate outperformed other SCFAs in alleviating allergic responses.
Jialu Shi   +11 more
wiley   +1 more source

Gut‐derived Lactobacillus from exceptional responders mitigates chemoradiotherapy‐induced intestinal injury through methionine‐driven epigenetic modulation

open access: yesiMeta, Volume 4, Issue 3, June 2025.
Using metagenomic sequencing and bioinformatics analysis of fecal samples from rectal cancer patients and corresponding mouse models, our study identifies a strong association between Lactobacillus abundance and acute chemoradiotherapy‐induced intestinal injury (ACRIII). Elevated Lactobacillus levels before treatment were consistently linked to reduced
Lu Yu   +16 more
wiley   +1 more source

Physiologically Based Pharmacokinetic Modeling and Simulation to Support a Change in the FDA‐Labeled Dosing Frequency of RHB‐105 Low‐Dose Rifabutin Triple Therapy for Helicobacter pylori Eradication

open access: yesThe Journal of Clinical Pharmacology, Volume 65, Issue 6, Page 779-786, June 2025.
Abstract Patient adherence is vital for Helicobacter pylori eradication. Simplifying therapy dosing schedules may promote patient adherence, enhance treatment success rates, and help mitigate the development of antibiotic resistance. We aimed to assess plasma and intragastric rifabutin, amoxicillin, and omeprazole concentrations comparing two dosing ...
Nimish Vakil   +6 more
wiley   +1 more source

Immune Reconstitution after Haploidentical Hematopoietic Stem Cell Transplantation with Different Non‐T‐Cell Depletion Protocols

open access: yesMedComm, Volume 6, Issue 6, June 2025.
This review examines immune reconstitution dynamics after haploidentical hematopoietic stem cell transplantation using different non‐T‐cell depletion protocols, including the Beijing and Baltimore protocols. It summarizes the reconstitution patterns of immune cell subsets and their correlation with posttransplant complications like relapse, GVHD, and ...
Xiao‐Di Ma   +2 more
wiley   +1 more source

Vaccines against sexually transmitted diseases [PDF]

open access: yes, 2003
BonDurant, Robert H   +3 more
core   +2 more sources

Critical Role of Skin in Pathogenesis: Bidirectional Crosstalk Between Skin and Multiple Organs

open access: yesMedComm – Future Medicine, Volume 4, Issue 2, June 2025.
The skin functions as both a protective barrier and an autonomous immune organ, maintaining dynamic interactions with internal organs. This review analyzes skin‐organ crosstalk mechanisms, highlighting key cytokines (particularly IL‐17A) and microbial metabolites that mediate interorgan communication.
Wende Deng   +7 more
wiley   +1 more source

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