Results 151 to 160 of about 349,968 (247)

Metal‐Supramolecular Drug Delivery System Empowered Meningeal Lymphatic Vessels‐Bridged Intracranial‐Peripheral Dual Immune Modulation for Reversing Glioblastoma Immune Suppression

open access: yesAdvanced Science, EarlyView.
A novel metal‐supramolecular nanoplatform (FLM@VC) enables efficient brain delivery via meningeal lymphatic vessels (MLVs), bypassing the blood‐brain barrier (BBB) through subcutaneous administration. It reprograms tumor‐associated macrophages (TAMs) and remodels the MLVs to promote DC trafficking and CD8+ T cell activation.
Chenxi Zhang   +11 more
wiley   +1 more source

Ulcerative colitis: signaling pathways, therapeutic targets and interventional strategies. [PDF]

open access: yesSignal Transduct Target Ther
Jia J   +7 more
europepmc   +1 more source

Polydopamine‐Encapsulated Probiotics Restore Gut Homeostasis and Reinstate Macrophage Efferocytosis in Systemic Lupus Erythematosus

open access: yesAdvanced Science, EarlyView.
Polydopamine‐encapsulated probiotics restore gut homeostasis and reinstate macrophage efferocytosis, thereby reestablishing immune tolerance and mitigating systemic autoimmunity, highlighting a bioengineered microbiota‐based therapeutic strategy for SLE.
Ruimiao Wu   +10 more
wiley   +1 more source

Chaihu-Shugan-San ameliorates chronic atrophic gastritis by inhibiting nuclear factor-kappa B-mediated inflammation and apoptosis. [PDF]

open access: yesWorld J Gastroenterol
Song J   +8 more
europepmc   +1 more source

Glucuronolactone Promotes Mucin Sulfation to Alleviate Deoxynivalenol‐Induced Intestinal Injury via Microbiota‐Dependent and ‐Independent AHR Activation

open access: yesAdvanced Science, EarlyView.
Glucuronolactone (GLU) as a natural metabolite of glucose, increases Lactobacillus amylovorus abundance and luminal IAA level to activate AHR signaling. In addition, GLU itself can directly elevate AHR signaling activity independently of microbiota and IAA.
Chenbin Cui   +8 more
wiley   +1 more source

Type 1 and CD103<sup>+</sup> Type 2 Conventional Dendritic Cells Are Decreased in Active Patients with Ulcerative Colitis but Not with Crohn's Disease. [PDF]

open access: yesEur J Immunol
Arribas-Rodríguez E   +18 more
europepmc   +1 more source

Innovative Metasurface Colorimetric Cell‐on‐a‐Chip Sensor for Continuous, Label‐Free, Non‐Destructive Assessment of Intestinal Barrier Dynamics

open access: yesAdvanced Science, EarlyView.
We developed a real‐time, label‐free, high‐throughput cell‐on‐a‐chip system based on a metasurface plasmon resonance colorimetric sensor (MetaSPRCS) to evaluate intestinal barrier function. This platform enables continuous monitoring of cell adhesion, proliferation, and barrier layer formation, disruption, and repair.
Youqian Chen   +14 more
wiley   +1 more source

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