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Mucosal Immunization with DNA Vaccines
Microbes and Infection, 1999The mucosal surface area of the gastrointestinal, genitourinary and respiratory tracts is more than 200 times greater than that of the skin and is the primary site of transmission of numerous diseases. The entry of pathogenic organisms at mucosal surfaces can be prevented by mucosal, but not systemic immunity.
M J, McCluskie, H L, Davis
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Mucosal Immunity in Allergic Rhinitis
Acta Oto-Laryngologica, 1993Secretory IgA (SIgA) is the main agent protecting the mucosal districts against both infectious microorganisms and inert foreign macromolecules. A lack of secretory immunity has previously been described in patients with allergic rhinitis, but it is a controversial finding.
CORTESINA G +5 more
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Stimulation of Mucosal Immunity
2003The mucosal immune system is composed of distinct regional immune tissue (e.g., "GALT," gut-associated lymphoid tissue; "BALT," bronchus-associated lymphoid tissue; reproductive tract and breast tissue, and so forth) interconnected by trafficking of primed lymphocytes as a common "mucosa-associated lymphoid tissue," "MALT" (1).
Lewis, DJ, Hayward, CM
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Advances in Dental Research, 1996
The mucosae form a barrier between our bodies and a hostile external environment. Diseases and extrinsic factors which impair mucosal function may lead to serious consequences. The mucosal immune system is the primary mediator of specific immunity at mucosal surfaces.
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The mucosae form a barrier between our bodies and a hostile external environment. Diseases and extrinsic factors which impair mucosal function may lead to serious consequences. The mucosal immune system is the primary mediator of specific immunity at mucosal surfaces.
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Induction of the Mucosal Immune Response
1989Exposure to antigens via mucosal membranes is well known to induce responses in the common mucosal system dominated by secretory IgA (SIgA), whereas parenterally given antigens are generally not considered to induce SIgA antibody production. Recent studies on the effect of vaccination suggests, however, that the antibody response patterns may be rather
Dahlgren, U +9 more
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2022
This chapter outlines the function of a mucosal tissue, including its role in detecting and combating pathogens that come into contact with mucosal surfaces. It describes the lymphoid tissue associated with mucosal surfaces and explains how it functions in a unique way to activate an immune response.
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This chapter outlines the function of a mucosal tissue, including its role in detecting and combating pathogens that come into contact with mucosal surfaces. It describes the lymphoid tissue associated with mucosal surfaces and explains how it functions in a unique way to activate an immune response.
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