Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj +23 more
wiley +1 more source
Bionic Technology in Prosthetics: Multi-Objective Optimization of a Bioinspired Shoulder-Elbow Prosthesis with Embedded Actuation. [PDF]
Jiang J, Chen G, Wang X, Yan H.
europepmc +1 more source
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz +9 more
wiley +1 more source
Multi-objective optimization design of microchannel reactors for Fischer-Tropsch synthesis using CFD, GENN, and NSGA-II. [PDF]
Ren S, Wang Y.
europepmc +1 more source
Efficient recovery from traumatic or degenerative diseases is a great challenge, even after all the advancements in bone and cartilage regeneration. Machine learning (ML) algorithms have presented opportunities to enhance these aspects by accurately analyzing imaging data.
Maryam Kamaei +9 more
wiley +1 more source
Performance driven multi objective optimization of 2 MW integrated Pseudo Direct Drive permanent magnet synchronous wind generator. [PDF]
Abdeljalil D +4 more
europepmc +1 more source
A heart‐on‐a‐chip model of dilated cardiomyopathy is developed from patient‐derived induced pluripotent stem cells. The model recapitulates key disease phenotypes and enables functional assessment through integrated bead‐based tracking and pillar deflection measurements.
Ali Mousavi +10 more
wiley +1 more source
Deep reinforcement learning-driven multi-objective optimization and its applications on lighting infrastructure operation and maintenance strategy. [PDF]
Wang Z +6 more
europepmc +1 more source
Tomographic Printing in a Chip: A Versatile Platform for Biomimetic 3D Organ‐on‐Chip
A novel light‐based bioprinting approach, TVAM‐in‐a‐chip, enables rapid, contactless fabrication of biomimetic 3D organ‐on‐chip devices directly within preassembled microfluidic platforms. This strategy supports diverse materials, including cell‐laden resins, and eliminates post‐assembly steps.
Riccardo Rizzo +3 more
wiley +1 more source
Optimization of ultrasound-assisted extraction of Sargassum polycystum for antitumor activity: Multi-objective optimization and mechanistic insights. [PDF]
Hou W +8 more
europepmc +1 more source

