Rethinking success, integrity, and culture in research (part 1) - a multi-actor qualitative study on success in science. [PDF]
Res Integr Peer Rev, 2021 Aubert Bonn N, Pinxten W.
europepmc +1 more source
Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang +10 more
wiley +1 more source
SPG4 and Dementia: Expanding the Clinical Spectrum
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
Disentangling urban sustainability: the Flemish City Monitor acknowledges complexity [PDF]
, 2010 Nowadays, cities have to deal with complexity. In this article we argue that the City Monitor for Sustainable Urban Development in the Flanders (Belgium) acknowledges complexity.
Block, Thomas, Van Assche, Joke
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao +6 more
wiley +1 more source
Perceptions of Fairness of Support Between Older Parents and Adult Children
Social SciencesIncreased life expectancy and reduced fertility mean more generations are living simultaneously but with fewer members. There is also a growing group of older people (aged 80 and over) who need care and support.
Anna Willems +2 more
doaj +1 more source
Building long-term vision for rural areas through multi-actor platforms: a preliminary study in the Emilia-Romagna region. [PDF]
Open Res Eur, 2021 Pellegrini E +3 more
europepmc +1 more source
[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich +19 more
wiley +1 more source
Varieties of public-private policy coordination: How the political economy affects multi-actor implementation. [PDF]
Public Policy Adm, 2021 Trein P, Tosun J.
europepmc +1 more source
Collective learning experiences in planning: the potential of experimental living labs [PDF]
, 2015 ‘Living labs’ originate from an R&D environment, and intend to innovate commodities by experience-based knowledge, with a direct involvement of users. Meanwhile, the living labs approach has been shifting into a wider range of applications, and has also ...
Dehaene, Michiel +2 more
core +1 more source