Results 31 to 40 of about 4,514,037 (280)

A Study of Religiosity and Lifestyle (Women over 20 in Tehran) [PDF]

open access: yesزن در فرهنگ و هنر, 2013
Lifestyles, since their emergence as constructive parts of modernity changes, have formed cultural and economic procedures and they even represent a quest for personal identity and have also affected social communications.
Mohammad Taghi Karami Ghahi   +1 more
doaj   +1 more source

Multivariate Monte-Carlo Simulation and Economic Valuation of Complex Financial Contracts: An Excel Based Implementation.

open access: yesSpreadsheets in Education, 2014
The economic valuation of complex financial contracts is often done using Monte-Carlo simulation. We show how to implement this approach using Excel. We discuss Monte-Carlo evaluation for standard single asset European options and then demonstrate how ...
Timothy J Kyng, Otto Konstandatos
doaj   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Deep Learning Artificial Neural Network for Pricing Multi-Asset European Options

open access: yesMathematics
This paper studies a p-layers deep learning artificial neural network (DLANN) for European multi-asset options. Firstly, a p-layers DLANN is constructed with undetermined weights and bias.
Zhiqiang Zhou   +4 more
doaj   +1 more source

Training neural networks to hedge multi-asset options

open access: yes
TRAINING NEURAL NETWORKS TO HEDGE MULTI-ASSET OPTIONS Training neural networks to hedge multi-asset options (1) Introduction (3) Literature Review (4) Deep Hedging (4) Stochastic Correlation (6) Methodology (8)
Zörényi, Márton   +2 more
openaire   +2 more sources

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Option Pricing in a Multi-Asset, Complete Market Economy [PDF]

open access: yesThe Journal of Financial and Quantitative Analysis, 2002
This paper extends the seminal Cox-Ross-Rubinstein ((1979), CRR hereafter) binomial model to multiple assets. It differs from previous models in that it is derived under the complete market environment specified by Duffie and Huang (1985) and He (1990).
Chen, Ren-Raw   +2 more
openaire   +1 more source

Upgrade Evaluation of Traffic Signal Assets: High-resolution Performance Measurement Framework

open access: yesPromet (Zagreb), 2018
Agencies that have large-scale traffic signal systems under their purview often have to face asset upgrade decisions. As one of the most advanced traffic control technologies, Adaptive Traffic Control Systems (ATCS) are among the options that must be ...
Igor Dakic   +3 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

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