Results 31 to 40 of about 4,514,037 (280)
A Study of Religiosity and Lifestyle (Women over 20 in Tehran) [PDF]
Lifestyles, since their emergence as constructive parts of modernity changes, have formed cultural and economic procedures and they even represent a quest for personal identity and have also affected social communications.
Mohammad Taghi Karami Ghahi +1 more
doaj +1 more source
The economic valuation of complex financial contracts is often done using Monte-Carlo simulation. We show how to implement this approach using Excel. We discuss Monte-Carlo evaluation for standard single asset European options and then demonstrate how ...
Timothy J Kyng, Otto Konstandatos
doaj +2 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Deep Learning Artificial Neural Network for Pricing Multi-Asset European Options
This paper studies a p-layers deep learning artificial neural network (DLANN) for European multi-asset options. Firstly, a p-layers DLANN is constructed with undetermined weights and bias.
Zhiqiang Zhou +4 more
doaj +1 more source
Training neural networks to hedge multi-asset options
TRAINING NEURAL NETWORKS TO HEDGE MULTI-ASSET OPTIONS Training neural networks to hedge multi-asset options (1) Introduction (3) Literature Review (4) Deep Hedging (4) Stochastic Correlation (6) Methodology (8)
Zörényi, Márton +2 more
openaire +2 more sources
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Option Pricing in a Multi-Asset, Complete Market Economy [PDF]
This paper extends the seminal Cox-Ross-Rubinstein ((1979), CRR hereafter) binomial model to multiple assets. It differs from previous models in that it is derived under the complete market environment specified by Duffie and Huang (1985) and He (1990).
Chen, Ren-Raw +2 more
openaire +1 more source
Upgrade Evaluation of Traffic Signal Assets: High-resolution Performance Measurement Framework
Agencies that have large-scale traffic signal systems under their purview often have to face asset upgrade decisions. As one of the most advanced traffic control technologies, Adaptive Traffic Control Systems (ATCS) are among the options that must be ...
Igor Dakic +3 more
doaj +1 more source
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source

