Results 31 to 40 of about 31,720 (216)

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

A multi attribute decision making method for selection of optimal assembly line [PDF]

open access: yesManagement Science Letters, 2011
With globalization, sweeping technological development, and increasing competition, customers are placing greater demands on manufacturers to increase quality, flexibility, on time delivery of product and less cost.
B. Vijaya Ramnath   +2 more
doaj  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Optimization of the nuclear accident emergency rescue plan selection based on a multiple-attribute decision

open access: yesFushe yanjiu yu fushe gongyi xuebao, 2022
An appropriate rescue plan can reduce the consequences and harm of a nuclear accident. Based on the combination of multi-attribute decision-making and cost-benefit analysis, alternative rescue schemes are ranked according to the rescue effect of a ...
DENG Duocheng   +5 more
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

The Probabilistic Dual Hesitant Fuzzy Multi-Attribute Decision-Making Method Based on Cumulative Prospect Theory and Its Application

open access: yesAxioms, 2023
Addressing the complex issue of multi-attribute decision-making within a probabilistic dual hesitant fuzzy context, where attribute weights are unknown, a novel decision-making method based on cumulative prospect theory is proposed, named the ...
Wenyu Zhang, Yuting Zhu
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Multi attribute decision making: assessing the technological and operational parameters of an aircraft

open access: yesTransport, 2010
Regional aircraft are playing a significant role in airline operations. This paper considers the problem of selecting an appropriate aircraft from the airline fleet for optimal regional air travel realization. Complexity balance between air travel demand
O. Čokorilo   +3 more
doaj   +3 more sources

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