Results 71 to 80 of about 13,680,796 (283)

An Integrated Assessment Approach as a Decision Support System for Urban Planning and Urban Regeneration Policies

Buildings, 2017
This paper focuses on an integrated multi-methodological evaluation process; it aimed at supporting public administrators in developing alternative strategies for intervention in urban planning and urban regeneration processes that focus on abandoned ...
Lucia Della Spina, Immacolata Lorè, Raffaele Scrivo, Angela Viglianisi   +3 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Cumulative Prospect Theory-Driven Pigeon-Inspired Optimization for UAV Swarm Dynamic Decision-Making

Drones
To address the dynamic decision-making and control problem in unmanned aerial vehicle (UAV) swarms, this paper proposes a cumulative prospect theory-driven pigeon-inspired optimization (CPT-PIO) algorithm. Gray relational analysis and information entropy
Yalan Peng, Mengzhen Huo
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Neurobiology of value integration: when value impacts valuation [PDF]

, 2011
Everyday choice options have advantages (positive values) and disadvantages (negative values) that need to be integrated into an overall subjective value.
J. Rieskamp, Rieskamp, Jörg, Park, S., Rieskamp, J., Kahnt, T., Heekeren, Hauke R., S. Q. Park, T. Kahnt, H. R. Heekeren, Kahnt, Thorsten, Heekeren, H., Park, Soyoung Q.   +11 more
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Assessing the empirical validity of alternative multi-attribute utility measures in the maternity context [PDF]

, 2009
Multi-attribute utility measures are preference-based health-related quality of life measures that have been developed to inform economic evaluations of health care interventions.
Morrell, Jane, Morrell Jane, Spiby Helen, Petrou, Stavros, Petrou Stavros, Spiby, Helen   +5 more
core   +1 more source

A Discretization Algorithm Based on Forest Optimization Network and Variable Precision Rough Set

Xibei Gongye Daxue Xuebao, 2020
Discretization of multidimensional attributes can improve the training speed and accuracy of machine learning algorithm. At present, the discretization algorithms perform at a lower level, and most of them are single attribute discretization algorithm ...

doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source