Results 171 to 180 of about 18,450 (254)

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

open access: yesAdvanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz   +9 more
wiley   +1 more source

A Modular Liver–Microbial Microfluidic Platform to Evaluate Therapeutic and Adverse Effects of Microbial Metabolites

open access: yesAdvanced Healthcare Materials, EarlyView.
This study introduces a modular microfluidic platform that connects liver cells with live microbes to mimic key aspects of the gut–liver interaction in steatosis. Using this system, both microbial metabolites and live bacteria significantly reduced fat accumulation in liver cells, but live microbes triggered inflammation and broader metabolic changes ...
Hsih‐Yin Tan   +7 more
wiley   +1 more source

A Transformer-LSTM Hybrid Detector for OFDM-IM Signal Detection. [PDF]

open access: yesEntropy (Basel)
Wang L   +9 more
europepmc   +1 more source

Bioprinting High‐Cell‐Density Cardiac Tissue Constructs With Sustained Contractile Function

open access: yesAdvanced Healthcare Materials, EarlyView.
Contractile cardiomyocytes in 3D culture provide insights into the behavior of the heart. Combining a 3D bioprinting approach with a multi‐electrode array allows the development of the 3D culture to be monitored over time, and matured cultures allow the effect of drugs on cardiac function to be modelled, replicating effects seen in clinical application.
Priscila Melo   +8 more
wiley   +1 more source

Encoded Cell‐Material Interactions to Reroute Cytokine Signaling for Regenerative Medicine

open access: yesAdvanced Healthcare Materials, EarlyView.
We present native MATRIX (Material Activated To Regulate Inducible gene eXpression), a co‐engineered material‐cell platform. Surfaces functionalized with antibodies for endogenous soluble ligands (e.g., IL‐1β or IL‐6) capture and immobilize ligands for presentation to a cognate, engineered synthetic Notch receptor, releasing a transcription factor (TF)
Zachary M. Eidman   +7 more
wiley   +1 more source

Open and shared sustainable mega-constellation. [PDF]

open access: yesNatl Sci Rev
Yang J   +14 more
europepmc   +1 more source

A Naphthalimide‐Based NIR‐Emissive AIE Photosensitizer for Synergistic Apoptosis/Ferroptosis‐Mediated Antitumor Therapy and Broad‐Spectrum Bacterial Inactivation With Rapid Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
An ionic naphthalimide AIE photosensitizer (PS), TPAPV‐NIM‐M, anchors to cellular and bacterial membranes, emits in the far‐red/near‐infrared (NIR) region, and efficiently generates reactive oxygen species (ROS) under white light. Its membrane‐localized photodynamic action drives apoptosis/ferroptosis‐mediated tumor suppression and broad‐spectrum ...
Sayed Mir Sayed   +3 more
wiley   +1 more source

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