Results 31 to 40 of about 857,449 (260)

Methods for Weighting Decisions to Assist Modelers and Decision Analysts: A Review of Ratio Assignment and Approximate Techniques

Applied Sciences, 2021
Computational models and simulations often involve representations of decision-making processes. Numerous methods exist for representing decision-making at varied resolution levels based on the objectives of the simulation and the desired level of ...
Barry Ezell, Christopher J. Lynch, Patrick T. Hester   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

THE CHOICE OF COMPACT FLUORESCENT LIGHT BULBS USING THE METHOD OF SAW AND CP [PDF]

Journal of Process Management and New Technologies, 2013
Multi-criteria analysis allows making decision in conflict conditions, when there are multiple alternatives and criteria, some of which should be maximized and some minimized. Therefore, in solving multicriteria tasks should use flexible instruments,
Ivana Zdravković, Momčilo Vujičić
doaj  

The impact of international institutions on Brussels: a multi‑criteria analysis approach

Brussels Studies, 2008
This paper develops an integrated assessment framework for costs and benefits related to the presence of international institutions in Brussels, Belgium.
Eric Corijn, Cathy Macharis, Theo Jans, Michel Huysseune   +3 more
doaj   +1 more source

Multi-Hazard Analysis in Gunungkidul Regency Using Spatial Multi-Criteria Evaluation

Forum Geografi, 2023
This study has two aims: to determine the spatial distribution of multi-hazard levels and to discover the interactions, interdependencies, and effects that cascade among hazards in Gunungkidul Regency, Special Region of Yogyakarta. A multi-hazard map was
Melati Mustikaningrum, Adrianus Farrel Widhatama, Khrisna Wasista Widantara, Mirza Ibrohim, Muhammad Fikri Hibatullah, Rinanda Amdalista Prastia Larasati, Sri Utami, Danang Sri Hadmoko   +7 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Multi-criteria analysis of urbanized area development concepts

Mokslas: Lietuvos Ateitis, 2023
The article deals with sustainable construction and the evaluation of its elements using Multi Criteria Decision Making (MCDM). The object of the research is the analysis of the concepts of the arrangement of the territory located in the Pilaitė ...
Viktorija Vitkauskienė
doaj   +1 more source

Applying multi-criteria analysis in a port system

Procedia Computer Science, 2017
Abstract This work presents a study developed in a medium port system composed of 50 public and private actors interacting with their macro-environment, which can generate strategic synergistic relationships. In order to determine these synergistic links between their components, the strategic phrases contained in their missions are analysed and ...
Claudia A. Durán, Fredi Edgardo Palominos, Felisa M. Córdova   +2 more
openaire   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source