Results 31 to 40 of about 2,777,487 (299)

Increasing discrimination in multi-criteria analysis [PDF]

, 2007
Multi criteria methods for supporting decision-making procedures are widely used in sustainability assessment. One of the most important steps in decision-making procedures is the evaluation of policy options or alternatives in order to find a hierarchy ...
Barannik, Valeriy, Blackwood, David J., Falconer, Ruth E.   +2 more
core  

Defining Roles in Pediatric Palliative Care: Perspectives From Oncology and Palliative Care Teams

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Early integration of pediatric palliative care (PPC) is associated with improved symptom management, quality of life, and healthcare utilization for children with cancer. Despite this, variation persists in how PPC is understood, operationalized, and integrated within pediatric oncology programs. In particular, ambiguity surrounding
Leeat Granek, Lori Wiener, Stephanie Veldhuijzen van Zanten, Donna Johnston, Fyeza Hasan, Adam Rapoport, Nathasha Datoo, Kimberley Widger, Sumit Gupta, Karen Fergus, Anthony K. C. Chan, Alisha Kassam, Emily McCullogh, Dave Lysecki   +13 more
wiley   +1 more source

Methods for Weighting Decisions to Assist Modelers and Decision Analysts: A Review of Ratio Assignment and Approximate Techniques

Applied Sciences, 2021
Computational models and simulations often involve representations of decision-making processes. Numerous methods exist for representing decision-making at varied resolution levels based on the objectives of the simulation and the desired level of ...
Barry Ezell, Christopher J. Lynch, Patrick T. Hester   +2 more
doaj   +1 more source

A Hybrid Multi-Criteria Analysis Model for Solving the Facility Location–Allocation Problem: a Case Study of Infectious Waste Disposal [PDF]

, 2018
Choosing locations for infectious waste disposal (IWD) is one of the most significant issues in hazardous waste management due to the risk imposed on the environment and human life. This risk can be the result of an undesirable location of IWD facilities.
Khokhajaikiat, P. (Porntep), Wichapa, N. (Narong)   +1 more
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Multi-Hazard Analysis in Gunungkidul Regency Using Spatial Multi-Criteria Evaluation

Forum Geografi, 2023
This study has two aims: to determine the spatial distribution of multi-hazard levels and to discover the interactions, interdependencies, and effects that cascade among hazards in Gunungkidul Regency, Special Region of Yogyakarta. A multi-hazard map was
Melati Mustikaningrum, Adrianus Farrel Widhatama, Khrisna Wasista Widantara, Mirza Ibrohim, Muhammad Fikri Hibatullah, Rinanda Amdalista Prastia Larasati, Sri Utami, Danang Sri Hadmoko   +7 more
doaj   +1 more source

Multi-criteria Anomaly Detection using Pareto Depth Analysis [PDF]

, 2012
We consider the problem of identifying patterns in a data set that exhibit anomalous behavior, often referred to as anomaly detection. In most anomaly detection algorithms, the dissimilarity between data samples is calculated by a single criterion, such ...
Calder, Jeff, Hero III, Alfred O., Hsiao, Ko-Jen, Xu, Kevin S.   +3 more
core  

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Public initiatives of settlement transformation. A theoretical-methodological approach to selecting tools of multi-criteria decision analysis [PDF]

, 2017
In Europe, the operating context in which initiatives of settlement transformation are currently initiated is characterized by a complex, elaborate combination of technical, regulatory and governance-related factors. A similar set of considerations makes
Battisti, Fabrizio, Chiovitti, Anthea, Guarini, Maria Rosaria   +2 more
core   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source