Results 61 to 70 of about 857,449 (260)

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird   +9 more
wiley   +1 more source

Multi-criteria analysis applied to railway rehabilitation

open access: yesMATEC Web of Conferences, 2018
The railway infrastructure has very specific constraints that lead to the need of maximizing of the availability of infrastructure, with high levels of safety and quality, associated with an optimized cost. Having said this, it is essential to understand
Caetano Vasco   +3 more
doaj   +1 more source

Multi-Year Program under Budget Constraints Using Multi-Criteria Analysis

open access: yesJournal of the Civil Engineering Forum, 2017
Road investment appraisal requires joint consideration of multiple criteria which are related to engineering, economic, social and environmental impacts.
Surya Adiguna   +2 more
doaj   +1 more source

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi   +17 more
wiley   +1 more source

A bibliometric data analysis of multi-criteria decision making methods in heritage buildings

open access: yesJournal of Civil Engineering and Management, 2019
Numerous countries are trying to find the best solution for conservation, restoration or reuse of the heritage buildings, preserving their cultural, historical, ethnic and spiritual values.
ŽydrÅ«nÄ— MorkÅ«naitÄ—   +2 more
doaj   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

Multi-criteria Analysis and Optimization in the AMPERE Ecosystem

open access: yesACM SIGAda Ada Letters
The AMPERE project is developing the next generation of high-performance and energy efficient Cyber-Physical Systems supporting multi-criteria optimization. This paper provides the general overview of the AMPERE approach to analyse and optimize parallel real-time applications in heterogeneous platforms. More specifically, it details how parallel OpenMP
Royuela, Sara   +10 more
openaire   +3 more sources

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro   +14 more
wiley   +1 more source

Multi criteria analysis for groundwater management using solar energy in Moghra Oasis, Egypt

open access: yesEgyptian Journal of Remote Sensing and Space Sciences, 2019
Egypt is facing a lack of water resources in addition to some diesel fuel supply problems which makes it necessary to rely more on renewable energy.
Ebtehal Sayed   +4 more
doaj   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs   +7 more
wiley   +1 more source

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