Results 71 to 80 of about 1,857,953 (354)
Multiple Criteria Decision Analysis (MCDA) for evaluating new medicines in Health Technology Assessment and beyond: the Advance Value Framework [PDF]
, 2017 Escalating drug prices have catalysed the generation of numerous “value frameworks” with the aim of informing payers, clinicians and patients on the assessment process of new medicines for the purpose of coverage and treatment selection decisions ...
Angelis, Aris, Kanavos, Panos
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Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Flood vulnerability assessment using a GIS‐based multi‐criteria approach—The case of Attica region
Journal of Flood Risk Management, 2020 The identification of flood‐prone areas is a fundamental component of rational urban planning and proper natural disaster management policy. The aim of the present study is to introduce a framework for the identification of flood‐prone areas using ...
Elissavet Feloni +2 more
doaj +1 more source
Reliability of water supplies in low and middle-income countries: A structured review of definitions and assessment criteria [PDF]
, 2018 The unreliability of water supplies in developing countries is a widely recognized concern. However, unreliability means different things in the variety of literature on water supplies, and no unified definition or assessment criteria exist.
Hunter, Paul R. +2 more
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Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Multi-criteria assesment of building integrated photovoltaics
Mokslas: Lietuvos Ateitis, 2015 To make reasonable solutions concerning integration of PV into the façade, complex assessment must be performed at the design stage of the building, taking into account all benefits and losses.
Violeta Motuzienė, Kęstutis Valančius
doaj +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
LandGreen infrastructure (GI) is increasingly prioritised in landscape policy and planning due to its potential to benefit ecosystems and enhance wildlife conservation. However, due to the uneven distribution of protected areas (PAs) and the fragmentation of
Álvaro Navas González +2 more
doaj +1 more source
Multi-criteria decision-making for sustainable metropolitan cities assessment
Journal of Environmental Management, 2018 The recent development of metropolitan cities, especially in Europe, requires an effective integrated management of city services, infrastructure, and communication networks at a metropolitan level. A preliminary step towards a proper organizational and management strategy of the metropolitan city is the analysis, benchmarking and optimization of the ...
Carli, Raffaele +2 more
openaire +2 more sources
A reliability based consistent fuzzy preference relations for risk assessment in oil and gas industry [PDF]
, 2019 In decision making, linguistic variables tend to be complex to handle but they make more sense than classical fuzzy numbers. Fuzziness is not sufficient enough to deal with information and degree of reliability of information is critical.
Abu Bakar, Ahmad Syafadhli +4 more
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