Results 41 to 50 of about 78,129 (256)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Applied SciencesShadows in hyperspectral images lead to reduced spectral intensity and changes in spectral characteristics, significantly hindering analysis and applications.
Yan Meng, Guanyi Li , Wei Huang
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
EntropyMulti-exposure image fusion (MEF) is a computational approach that amalgamates multiple images, each captured at varying exposure levels, into a singular, high-quality image that faithfully encapsulates the visual information from all the contributing ...
Yuhui Huang +4 more
doaj +1 more source
IEEE Photonics Journal, 2019 Generally, the dynamic range of night vision scenes is large. Owing to the limited dynamic range of traditional low light imaging technology, the captured images are always partially overexposed or underexposed.
Guo Chen +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Halo-Free Multi-Exposure Image Fusion Based on Sparse Representation of Gradient Features
Applied Sciences, 2018 Due to sharp changes in local brightness in high dynamic range scenes, fused images obtained by the traditional multi-exposure fusion methods usually have an unnatural appearance resulting from halo artifacts.
Hua Shao +6 more
doaj +1 more source
Application and prospects of AI-based radiomics in ultrasound diagnosis
Visual Computing for Industry, Biomedicine, and Art, 2023 Artificial intelligence (AI)-based radiomics has attracted considerable research attention in the field of medical imaging, including ultrasound diagnosis.
Haoyan Zhang +4 more
doaj +1 more source