Results 81 to 90 of about 38,382 (244)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Leveraging waste-based additives and machine learning for sustainable mortar development in construction

open access: yesReviews on Advanced Materials Science
This study presents a novel data-driven approach to improving the compressive strength (C-S) of environmentally friendly rubberized mortar that incorporates ingredients that are in line with current sustainability objectives in construction: glass powder,
Zhang Yi   +4 more
doaj   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

open access: yesFEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai   +8 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Joint beamforming for multiuser SCFDE block transmission system in frequency selective MIMO channels

open access: yesTongxin xuebao, 2013
Single carrier frequency domain equalization (SCFDE) joint beamforming in frequency selective multiple input multiple output (MIMO) channels under the multi-user scenario was analyzed.Firstly,the frequency domain beamforming was transformed to a time ...
Li-zhou Xu   +3 more
doaj   +2 more sources

Artificial intelligence-based multi-expression programming prediction of magnetized radiative nanofluid flow between coaxial deformable tubes

open access: yesCase Studies in Thermal Engineering
This research primarily focuses on improving the thermal efficiency of blood between the two coaxial tubes utilizing silver nanomaterials. Endoscopy is used to detect the inner diseases of body that are complex to detect from the ordinary visualization ...
Bilal Ahmed   +6 more
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Data-Driven Insights into Concrete Flow and Strength: Advancing Smart Material Design Using Machine Learning Strategies

open access: yesBuildings
Concrete plays a pivotal role in modern methods of construction due to its enhanced strength, durability, and adaptability to advanced building technologies.
Muwaffaq Alqurashi
doaj   +1 more source

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