Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs
Advanced Science, EarlyView.Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou +22 more
wiley +1 more source
Applied SciencesThis study analyzed the effects of changes in the inter-floor noise assessment system in multi-family housing in Korea on heavy-weight impact sound performance assessment.
Hee-Mo Goo, Soon-Seong Moon, Jun-Oh Yeon
doaj +1 more source
THE CONCEPTS ON QUALITY OF LIFE IN THE MARIBOR POST-WW2 HOUSING ESTATES [PDF]
AR: Arhitektura, Raziskave, 2012 The paradigm of quality of life in housing depends on variousinterconnectedness functions, which satisfy not only the needsof dwellers but also the inhabitants of the city, in general.
Vanja Skalicky, Metka Sitar
doaj
Engaging as Partners in Energy Efficiency: A Primer for Utilities on the Energy Efficiency Needs of Multifamily Buildings and Their Owners [PDF]
, 2013 The multifamily building sector presents a unique set of challenges and opportunities for utilities seeking to implement effective energy efficiency programs.
Anne McKibbin
core
Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain
Advanced Science, EarlyView.This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao +7 more
wiley +1 more source
Apparent water loss prevention using modern measurement tools
E3S Web of Conferences, 2017 The problem of discrepancies in balancing housing water meters indications in relation to the main water meters in multi-housing/family building is well known to both, property owners as well as to water supply and sewage companies.
Gwoździej-Mazur Joanna
doaj +1 more source
Housing and Mobility Toolkit for San Mateo County [PDF]
, 2019 Since the end of the Great Recession, San Mateo County has attracted new workers at a record rate without building anywhere near enough housing. This jobs-housing imbalance drives the cost of housing up and forces many moderate and lower-income employees
Alexander, Serena +8 more
core +1 more source
β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma
Advanced Science, EarlyView.β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto +20 more
wiley +1 more source
The Influence of Parking-Derived Structural Grid on Apartment Organisation
BuildingsIn contemporary multi-family housing construction, the structural grid is often influenced or conditionally determined by the dimensional logic of underground parking garages. When transferred to above-ground storeys, it directly defines façade frontage,
Đorđe Alfirević +3 more
doaj +1 more source
Potential Economic Consequences of Local Nonconformity to Regional Land Use and Transportation Plans Using a Spatial Economic Model [PDF]
, 2011 To achieve the greenhouse gas (GHG) reduction targets that are required by California’s global warming legislation (AB32), the state of California has determined that recent growth trends in vehicle miles traveled (VMT) must be curtailed.
Abraham, John E. +3 more
core +1 more source