Results 191 to 200 of about 7,498,046 (298)

Energy Efficiency in Multi-Family Residential Buildings in Latvia. Costs Benefit Analysis Comparing Different Business Models

Energy Performance Contracts (EPCs) are very seldom used in the residential sector, especially for deep renovation of multi-family buildings. Only up to 10% of energy service companies’ activities are targeted in the sector.
Zvaigznītis, Kristaps, Rochas, Claudio, Kamenders, Agris, Žogla, Gatis   +3 more
core  

Find your village: co-designing a community asset-based peer support intervention for wellbeing, social connectedness, and early child development among migrant families during the first 1001 days. [PDF]

Glob Health Action
Allport T, Musse S, Ingram J, Feder G, Osman F, Redwood S.   +5 more
europepmc   +1 more source

Tracking CDK1 Dynamics With a Novel Biosensor Mouse and Clinical Cohorts to Predict CDK4/6 Inhibitor Sensitivity in ER+ Breast Cancer

Advanced Science, EarlyView.
Cyclin‐dependent kinase (CDK) 1 activity is a dynamic marker of treatment response in estrogen receptor positive breast cancer. Patient cohorts reveal CDK1 activity increases during progression to invasive disease, where high expression correlates with poor survival. Using a novel Cdk1 biosensor mouse alongside in vitro models, we demonstrate that CDK1
Sarah Alexandrou, Kristine J. Fernandez, Min Li Huang, Ewan K. A. Millar, Claire Vennin, Leila Eshraghi, Tan Dat Timothy Lam, Victoria Lee, Nyah C. Brooks, Janett Stoehr, Cristian Guaman Mendez, Douglas Strathdee, David Stevenson, David Herrmann, Sandra O'Toole, Paul Timpson, Max Nobis, C. Elizabeth Caldon   +17 more
wiley   +1 more source

Dental-Legal Partnerships: Extending the Medical-Legal Partnership Model to Dentistry. [PDF]

J Public Health Dent
Testa A, Mungia R, Tsai J.
europepmc   +1 more source

SCTR–Expressing Astrocyte–Serotonergic Neuron Signaling Drives Sexual Dimorphism in Depression Through KAT7/H4ac–Foxc2 Epigenetic Axis in an AMPK‐Dependent Manner

Advanced Science, EarlyView.
Astrocytic SCTR modulates depressive‐related phenotypes via AMPKα1, whereas lowered Mt1 blunts Megalin‐dependent AMPKα2 signaling in serotonergic neurons. Diminished AMPKα2 hinders KAT7 nuclear translocation, curtails KAT7 occupancy and H4K8ac at the Foxc2 promoter, and represses Foxc2 transcription, revealing cell‐type‐specific AMPK‐linked epigenetic ...
Fantao Meng, Jing Liu, Juanjuan Dai, Min Wu, Wentao Wang, Mengdi Zhang, Shujun Jiang, Yifan Cao, Lihong Xu, Lin Du, Dan Wang, Di Zhao, Gaofeng Qin, Dong Wang, Wei Li, Chen Li   +15 more
wiley   +1 more source

Development and psychometric evaluation of a new itch assessment questionnaire for use in multi-ethnic Asian population. [PDF]

Qual Life Res
Moosa AS, Tan NC, Chen R, Ng DX, Choo KJL, Tay YK, Luo N.   +6 more
europepmc   +1 more source

Low‐Intensity Ultrasound‐Triggered Microbubble Cavitation Attenuates Diabetic Kidney Injury Partially by Reversing Endothelial Dysfunction

Advanced Science, EarlyView.
Non‐invasive low‐intensity pulsed ultrasound ‐triggered cavitation of clinically approved diagnostic‐grade microbubbles delivers favorable mechanical stimuli to renal microvasculature. This intervention restores renal microvascular homeostasis, alleviates DKD‐associated histological and functional damage, and suppresses inflammatory and fibrotic ...
Yubo Lai, Liang Zhang, Wenxin Tao, Jieyuan An, Lantian Wang, Zhaoyou Liu, Guodong Yang, Pengying Wu, Lijun Yuan   +8 more
wiley   +1 more source

Maintaining smoke-free homes in Germany: a hypothesis-generating qualitative study of women's experiences across social and household contexts. [PDF]

BMJ Open
Barrera B, Feliu A, Espina C, Brand T, Zeeb H, Rees VW.   +5 more
europepmc   +1 more source

Extracellular Vesicle Packaged TDP43 Derived From ECs Exacerbates Cigarette Tar‐Related Atherosclerosis Progression via Enhancing Macrophage Extracellular Traps

Advanced Science, EarlyView.
Cigarette tar triggers EC‐derived EVs carrying TDP43, which binds VDAC1 to boost MAMs, mitochondrial Ca2+ overload, and METs formation in macrophages, accelerating smoking‐related AS progression, while retinoic acid binds TDP43 to block this pathogenic cascade.
Xinxin Zhu, Yuwu Chen, Wei Meng, Biyi Xu, Junke Mou, Xiaolin Liu, Mengyang Wang, Qishuo Gu, Qianhui Sun, Man Li, Chen Zhao, Ming Zeng, Ying Lv, Boling Yi, Sheng Qu, Xiaoxuan Bai, Ji Li, Xing Luo, Sining Hu, Bo Yu, Haibo Jia   +20 more
wiley   +1 more source

Measuring Neighborhood Socioeconomic Status from Sky and Street: An Ensemble Learning Framework. [PDF]

Trans Urban Data Sci Technol
Li Y, Long Y, Suel E, Zhang Y, Robinson BE, Cavanaugh AC, Su N, Ezzati M.   +7 more
europepmc   +1 more source