Results 51 to 60 of about 267,918 (212)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Tatar identity: current state and perspectives
Историческая этнология, 2016 Identity processes take place in different sociopolitical conditions and depend upon their contexts. Since the social crisis and the associated identity crisis, Russian society has been faced with the task of forming a new common country identity that ...
Rafael S. Khakimov
doaj
Formation of Project Identity in a Multi-Project Environment [PDF]
International Journal of Management, Knowledge and Learning, 2020 Managing multiple projects concurrently is an effective way to handle modern business projects. However, management of project multiplicity is still a challenge in the construction industry, and the project identity is considered fundamental for ...
Emmanuel Nyameke +2 more
doaj
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Nordic Journal of Migration Research, 2011 This article discusses how second-generation identities are negotiated in the intersection of multi-ethnic realities of everyday life in Helsinki and often multi-sited kin-based transnational ties.
Lotta Haikkola
doaj +1 more source
Co-design Optimization of a Novel Multi-identity Drone Helicopter (MICOPTER). [PDF]
J Intell Robot Syst, 2022 Abedini A, Bataleblu AA, Roshanian J.
europepmc +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
British Identity in the 1990s–2020s in the Context of Multi- and Interculturalism
Известия Уральского федерального университета. Серия 2: Гуманитарные наукиThis article presents the results of a study of the discourse of British identity formed between the 1990s and 2020s and includes, in addition to elements of “indigenous” British culture, foreign ethnic elements introduced by immigration — in the context
Dina Nikolaevna Karavaeva +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source