Results 141 to 150 of about 3,113,449 (308)

An Analysis of Chaining in Multi-Label Classification

open access: yes, 2012
The idea of classifier chains has recently been introduced as a promising technique for multi-label classification. However, despite being intuitively appealing and showing strong performance in empirical studies, still very little is known about the main principles underlying this type of method.
Krzysztof Dembczynski   +2 more
openaire   +2 more sources

Multi-View Multi-Label Classification via View-Label Matching Selection

open access: yes
In multi-view multi-label classification (MVML), each object is described by several heterogeneous views while annotated with multiple related labels. The key to learn from such complicate data lies in how to fuse cross-view features and explore multi ...
Yang, Zhen   +5 more
core   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Online discriminative dictionary learning via label information for multi task object tracking

open access: yes, 2014
In this paper, a supervised approach to online learn a structured sparse and discriminative representation for object tracking is presented. Label information from training data is incorporated into the dictionary learning process to construct a compact ...
Fan BJ(范保杰)   +3 more
core  

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

A new era in retail: Private-label production by national-brand manufacturers and premium-quality private labels. [PDF]

open access: yes
Private labels have witnessed considerable growth in grocery retailing. While existing academic studies have provided valuable insights concerning the evolution of private labels, several issues remain largely unexplored.
Braak, A.M. ter
core  

Label-dependent splitting for multi-label data

open access: yes, 2023
Thesis (PhD)--Stellenbosch University, 2023.ENGLISH SUMMARY: Multi-label classification problems arise in scenarios where every data case can be associated with multiple labels simultaneously.
Muller, Annegret
core  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

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