Results 131 to 140 of about 16,062,156 (297)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Detecting cancer regions in histopathology using multi-level features

, 2012
Visual detection of cancerous areas within histopathological samples is still a problematic task, since it strongly relies on complex qualitative, thus highly subjective, analyses performed by expert histopathologists.
BEVILACQUA, ALESSANDRO, S. Bravaccini, GHERARDI, ALESSANDRO, C. Busa   +3 more
core   +1 more source

PECSA Net: Pupil Segmentation Using Attention Integrated Encoder-based Multi-Level Feature Extractor for Analysis of Ocular Dynamics

Current Directions in Biomedical Engineering
Pupillometry is considered as an emerging technique for analysing the dynamic variations of pupil structure non-invasively. Delineation of the pupil region from ocular images plays a crucial role in the prediction of microexpressions and subtle ...
Choyichivayalil Arya, Veluswamy Pandiyarasan, Palanisamy Rohini   +2 more
doaj   +1 more source

Multi-level feature fusion network for neuronal morphology classification

Frontiers in Neuroscience
Neuronal morphology can be represented using various feature representations, such as hand-crafted morphometrics and deep features. These features are complementary to each other, contributing to improving performance. However, existing classification methods only utilize a single feature representation or simply concatenate different features without ...
Chunli Sun, Feng Zhao
openaire   +3 more sources

TopoLayout: Multi-level graph layout by topological features

, 2007
We describe TopoLayout, a feature-based, multi-level algorithm that draws undirected graphs based on the topological features they contain. Topological features are detected recursively inside the graph, and their subgraphs are collapsed into single ...
Daniel Archambault, David Auber, Archambault, Daniel, Auber, David, Tamara Munzner, Munzner, Tamara   +5 more
core  

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Attention-based interactive multi-level feature fusion for named entity recognition

Scientific Reports
Named Entity Recognition (NER) is an essential component of numerous Natural Language Processing (NLP) systems, with the aim of identifying and classifying entities that have specific meanings in raw text, such as person (PER), location (LOC), and ...
Yiwu Xu, Yun Chen
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source