Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu +10 more
wiley +1 more source
Multi-level governance, governance roles and institutional entrepreneurship in public policies
, 2011 The hypothesis advanced in the paper is that the effectiveness of multi-level governance in achieving given policy-objectives in a given context depends on the performance of the individuals who, being in a boundary position, connect the different levels
DE VIVO, PAOLA, Cerase F. P., Sacco E.
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective CDKL5 deficiency disorder (CDD) is a rare, severe developmental and epileptic encephalopathy. There is a pressing need to develop effective and sustainable therapeutic strategies. We aimed to investigate the causal association between febrile episodes and epileptic seizures for therapeutic implications in CDD patients.
Siyi Wang +13 more
wiley +1 more source
Rethinking marine plastics pollution: Science diplomacy and multi-level governance. [PDF]
Int Rev Adm SciBeltran M +4 more
europepmc +1 more source
Collaborative governance in the Quebec Cancer Network: a realist evaluation of emerging mechanisms of institutionalization, multi-level governance, and value creation using a longitudinal multiple case study design. [PDF]
BMC Health Serv Res, 2019 Tremblay D +11 more
europepmc +1 more source
Arthritis Care &Research, EarlyView.Objective We aimed to estimate the prevalence and cumulative incidence of hydroxychloroquine retinopathy (HCQ‐R) and its risk factors among patients receiving long‐term HCQ with rheumatic diseases through a systematic review and meta‐analysis of observational studies that used spectral‐domain optical coherence tomography (SD‐OCT) for screening ...
Narsis Daftarian +4 more
wiley +1 more source
Securitization versus sovereignty? Multi-level governance, scientific objectivation, and the discourses of the Canadian and American heads of state during the first wave of the COVID-19 pandemic. [PDF]
Int JLamontagne M.
europepmc +1 more source
Arthritis Care &Research, EarlyView.Objective To support high‐quality, patient‐centered care for systemic lupus erythematosus (SLE), the American College of Rheumatology (ACR) developed evidence‐based measures incorporating clinical and patient‐reported outcome measures (PROMs). Using the Consolidated Framework for Implementation Research (CFIR), we conducted semistructured interviews ...
Catherine Nasrallah +13 more
wiley +1 more source
Multi-actor regional governance: regions as new players for innovation in Europe [PDF]
In recent years, new regionally based strategy building processes emerged at the interface between public policy and the social coordination of collective action. Foresight as a governance process for stimulating regional innovation and for strengthening
Vivien Lo, Knut Koschatzky
core
Anorectal Dysfunction in Systemic Sclerosis: Clinical Phenotypes and Functional Patterns
Arthritis Care &Research, EarlyView.Objective The aim of this study was to characterize specific physiologic defects in anorectal dysfunction in systemic sclerosis (SSc) using anorectal manometry (ARM), evaluate associations with gastrointestinal (GI) and extraintestinal clinical phenotypes, and explore potential serologic markers for risk stratification.
Timothy Kaniecki +6 more
wiley +1 more source