Results 101 to 110 of about 845,538 (282)

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento   +3 more
wiley   +1 more source

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi   +5 more
wiley   +1 more source

Production Planning with The Neutrosophic Fuzzy Multi-Objective Optimization Technique [PDF]

open access: yesNeutrosophic Sets and Systems
Businesses want to realize their production at the desired time and quality. In addition, businesses aim to use their existing resources efficiently and increase their earnings.
Şule Bayazit Bedirhanoğlu   +1 more
doaj   +1 more source

Evolutionary Multi-Objective Robust Optimization

open access: yes, 2008
This work presented and tested an optimization procedure that takes into account robustness in multi-objective optimization. It was shown that the method is able to deal with different types of problems and with different degrees of complexity. The extension of the robust Pareto frontier can be controlled by the Decision Maker by making use of a ...
Ferreira, J.   +3 more
openaire   +4 more sources

Validation of the Pediatric Arthritis Ultrasound Scoring System for the Elbow, Wrist, and Finger Joints in Children With Juvenile Idiopathic Arthritis

open access: yesArthritis Care &Research, EarlyView.
Objective We aimed to validate the Pediatric Arthritis Ultrasound Scoring System (PAUSS) for upper extremity joints in children with juvenile idiopathic arthritis (JIA). Methods Children with JIA were evaluated for elbow, wrist, or finger arthritis by clinical examination (CE) and musculoskeletal ultrasound (MSUS) with images scored according to the ...
Patricia Vega‐Fernandez   +12 more
wiley   +1 more source

Multi-objective path optimization for arc welding robot based on discrete DN multi-objective particle swarm optimization

open access: yesInternational Journal of Advanced Robotic Systems, 2019
Rational weld seams sequence is important for improving welding productivity and quality. Hence, intelligent path optimization strategy is introduced to obtain optimized weld seams sequence in this article.
Wang Xue-Wu, Min Yong, Gu Xing-sheng
doaj   +1 more source

Single-objective and multi-objective optimization using the HUMANT algorithm

open access: yesCroatian Operational Research Review, 2015
When facing a real world, optimization problems mainly become multi-objective i.e. they have several criteria of excellence. A multi-criteria problem submitted for multi-criteria evaluation is a complex problem, as usually there is no optimal solution ...
Marko Mladineo   +2 more
doaj   +1 more source

Risk of Retinopathy Associated with Long‐Term Use of Hydroxychloroquine in Patients with Rheumatic Diseases: A Systematic Review and Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective We aimed to estimate the prevalence and cumulative incidence of hydroxychloroquine retinopathy (HCQ‐R) and its risk factors among patients receiving long‐term HCQ with rheumatic diseases through a systematic review and meta‐analysis of observational studies that used spectral‐domain optical coherence tomography (SD‐OCT) for screening ...
Narsis Daftarian   +4 more
wiley   +1 more source

Multi-objective/loading optimization for rotating composite flexbeams [PDF]

open access: yes
With the evolution of advanced composites, the feasibility of designing bearingless rotor systems for high speed, demanding maneuver envelopes, and high aircraft gross weights has become a reality.
Hamilton, Brian K., Peters, James R.
core   +1 more source

Developing and Evaluating a Laboratory‐Based Frailty Index (FI‐Lab) for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

open access: yesArthritis Care &Research, Accepted Article.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical frailty index (FI).
Grace Burns   +2 more
wiley   +1 more source

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