Results 181 to 190 of about 845,538 (282)

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

Advanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat, Johan Sebastian Lopez‐Parra, Willem M. H. Hoogaars, Emma Dijkstra, Cynthia Huang, Irafasha C. Casmil, Anna K. Blakney, Peter Olinga, Barbara Rothen‐Rutishauser, Hélder A. Santos, Alke Petri‐Fink, Flávia Sousa   +11 more
wiley   +1 more source

Optimization of ultrasound-assisted extraction of Sargassum polycystum for antitumor activity: Multi-objective optimization and mechanistic insights. [PDF]

Ultrason Sonochem
Hou W, Qin C, Zhang L, Yu K, Lu J, Qin M, Hao E, Deng J, Hou X.   +8 more
europepmc   +1 more source

In Situ 3D Bioprinting: Impact of Cross‐Linking on the Adhesive Properties of Hydrogels

Advanced Functional Materials, EarlyView.
In situ 3D bioprinting enables the direct deposition of cell‐laden, adhesive biomaterials for on‐site tissue regeneration. This review provides a comprehensive overview of how cross‐linking influences the bioadhesive properties of hydrogels used in 3D bioprinting, highlighting cross‐linking triggers, bioadhesion mechanisms, polymer interpenetration ...
Odile Romero Fernandez, Mulazim Hussain Asim, Shumaila Arshad, Gergely Kali, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

Adaptive airspace allocation model for urban drone logistics using multi-objective optimization under uncertainty. [PDF]

Sci Rep
Zhu Y, Sun X, Hou T.
europepmc   +1 more source

Anomalous Pressure‐Temperature Ultrahigh Sensitivities in Atomically Engineered Carbonitride MXenes for Multifunctional Wearable Human–Machine Interfaces: Joint Computational–Experimental Elucidations

Advanced Functional Materials, EarlyView.
Atomically engineered layered 2D Ti3CNTz carbonitride MXene exhibits ultrahigh heat and pressure sensitivity, enabling dual‐mode sensors with 300%–400% performance enhancement and durability for real‐time health‐monitoring interface devices. Precise nitrogen incorporation (e.g., Ti3C1.8N0.2Tz) boosts conductivity, enhancing temperature response, while ...
Debananda Mohapatra, Ju‐Hyoung Han, Hyun Jin Kang, Jeong Eun Byun, Seonghun Lee, Sanghyuk Lee, Yeseul Son, Jaeeun Park, Tae Joo Shin, Youngho Kang, Jung Woo Lee, Soon‐Yong Kwon, Soo‐Hyun Kim   +12 more
wiley   +1 more source

Multi-objective optimization of hybrid laser cleaning process parameters for carbon deposits based on bayesian-SVR and NSGA-II. [PDF]

Sci Rep
Su Y, Hu Y, Zhang Q, Yao Z, Chen Z, Yin Y, Yang Z, Yao J.   +7 more
europepmc   +1 more source

Additive Manufacturing of NiTi Shape Memory Alloys for Elastocaloric Applications: A Review

Advanced Functional Materials, EarlyView.
Additive manufacturing enables complex NiTi architectures that overcome key limitations in elastocaloric refrigeration, including poor heat transfer and high mechanical work input. This review surveys recent advances in LPBF‐ and DED‐fabricated NiTi shape memory alloys for elastocaloric applications, highlighting process–structure–performance ...
Ignatius Andre Setiawan, Mohammad Mehrali, Jaka Tušek, Shiva Mohajerani, Xiebin Wang, Dermot Brabazon, Mohammad Elahinia, Mehrshad Mehrpouya   +7 more
wiley   +1 more source

A Hybrid Fuzzy-PSO Framework for Multi-Objective Optimization of Stereolithography Process Parameters. [PDF]

Micromachines (Basel)
Al-Khafaji MMH, Kadauw AAA, Abdulrazaq MM, Al-Khafaji HMH, Zeidler H.   +4 more
europepmc   +1 more source

The Cuttlebone Blueprint for Multifunctional Metamaterials: Design Taxonomy, Functional Decoupling, and Future Horizons

Advanced Functional Materials, EarlyView.
Cuttlebone‐inspired metamaterials exploit a septum‐wall architecture to achieve excellent mechanical and functional properties. This review classifies existing designs into direct biomimetic, honeycomb‐type, and strut‐type architectures, summarizes governing design principles, and presents a decoupled design framework for interpreting multiphysical ...
Xinwei Li, Zhendong Li
wiley   +1 more source

Lightweight Design Method for Micromanufacturing Systems Based on Multi-Objective Optimization. [PDF]

Micromachines (Basel)
Li S, Hashemi Sohi SH.
europepmc   +1 more source