Results 41 to 50 of about 6,133,638 (273)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Efficient decomposition-based algorithm to solve long-term pipeline scheduling problem

Petroleum Science, 2019
This paper addresses the scheduling and inventory management of a straight pipeline system connecting a single refinery to multiple distribution centers.
S. Moradi, S. A. MirHassani, F. Hooshmand   +2 more
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Floatation of Buried Submarine Pipeline under Cyclic Loading of Water Pressure -Numerical and Experimental Studies- [PDF]

, 2000
A dynamic response of a submarine pipeline buried in sandy seabed sediments to water loading generated by harmonically oscillating water-table vertical movements is examined in the present report experimentally and numerically.
Maeno, Shiro, Magda, Waldemar, Nago, Hiroshi   +2 more
core   +1 more source

Computational Fluid Dynamics based Flow Diagnostics in Hydraulic Capsule Pipeline Bends [PDF]

Hydraulic Capsule Pipelines (HCPs) are the third generation of pipelines that are based on the transport of hollow spherical, or cylindrical, capsules by the force exerted on them from the carrier fluid, which is water.
Asim, Taimoor, Mishra, Rakesh
core   +3 more sources

Hybrid Machine Learning and Nature-Inspired Optimization for Robust and Accurate Product Recommendations

ITEGAM-JETIA
The rapid evolution of e-commerce and consumer behaviour demands intelligent and accurate product recommendation systems. This research presents a dual-path hybrid framework that integrates advanced machine learning and quantum-inspired techniques for ...
V. Jenifer, T. Kamala Kannan
doaj   +1 more source

Ultrasonic Guided Wave Method For Crack Detection In Buried Plastic Pipe

MATEC Web of Conferences, 2016
Plastic pipe are widely used in many fields for the fluid or gaseous product conveyance but basic components of a plastic material made it very sensitive to damage, which requires techniques for detecting damage reliable and efficient.
Wan Hamat Wan Sofian, Ghazali Mohd Fairusham, Priyandoko Gigih   +2 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Shapley value cost allocation model for multimodal freight transport carriers

Transport Technologies
The downstream petroleum products distribution is beset with significant challenges due to ageing pipeline infrastructure, pipeline vandalism and other logistical constraints.
Harrison Obiora Amuji, Donatus Eberechukwu Onwuegbuchunam, Kenneth Okechukwu Okeke, John Folayan Ojutalayo, Christy Chidiebere Nwachi, Abdulmalik Muhammad Mustapha   +5 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source