Results 251 to 260 of about 781,103 (334)

Androgen Receptor‐Induced Lactoferrin Accelerates Prostate Tumorigenesis Through Modulating Ferroptosis

Advanced Science, EarlyView.
This study demonstrates that transcription factor androgen receptor (AR) directly binds the LF promoter, driving lactoferrin overexpression to promote ferritin (FTH1/FTL) upregulation and inhibit p53‐ALOX12‐mediated ferroptosis in prostate cancer. Lactoferrin could be a new potential therapeutic target in prostate cancer.
Can Liu, Qiu Peng, Xiaoyue Zhang, Zhengshuo Li, Yangge Wu, Yuqing Wen, Run Zheng, Shuanglong Wu, Chenfei Zhou, Zhengyu Hu, Lanjun Shu, Xinyi Ma, Qiuyang Li, Ya Ma, Chunlin Ou, Ming Zhao, Songqing Fan, Lingyu Wei, Jian Ma   +18 more
wiley   +1 more source

Multi-scale entropy analysis of acoustic emission for gearbox fault severity classification. [PDF]

Sci Rep
Sánchez RV, Liu Y, Qin H, Cerrada M, Cabrera D, Carrasquero E, Medina R.   +6 more
europepmc   +1 more source

Full‐Body AI Agent: A Perspective on Multi‐Scale Collaborative AI for Systemic Biology and Precision Medicine

Advanced Science, EarlyView.
We propose the Full‐Body AI Agent, a multi‐scale collaborative framework with 7 biological‐layer agents. It unifies multi‐omics/clinical data via standardized protocols, enabling phenotype‐guided closed‐loop reasoning, quantitative evaluation, and LLM safeguards, with promising applications in tumor metastasis modeling and precision drug development ...
Aoqi Wang, Jiajia Liu, Jianguo Wen, Yangyang Luo, Zhiwei Fan, Liren Yang, Xi Hu, Ruihan Luo, Yankai Yu, Sophia Li, Weiling Zhao, Xiaobo Zhou   +11 more
wiley   +1 more source

SparsePool: A Graph Pooling Framework via Sparse Representation for Graph Classification. [PDF]

Sensors (Basel)
Li Z, Zhai X, Hu H, Liang J, Hu G.
europepmc   +1 more source

Facies classification and channel detection for reservoir characterization using self-organizing maps in geologically complex Groningen gas field, the Netherlands. [PDF]

Sci Rep
El-Attar S, El-Werr AK, Abdel-Rahman EM, Sobhy MN.   +3 more
europepmc   +1 more source

Hybrid deep learning framework integrating CNNs, transformers, and adaptive optimization for accurate suspended sediment concentration prediction. [PDF]

Sci Rep
Fan J, Li R, Qi S, Zong H, Zhao M.
europepmc   +1 more source

A Discriminative Enhancement and Selective Fusion Method for Low-Light Cross-Spectral Object Detection. [PDF]

Sensors (Basel)
Yang P, Jiang J, Zhang Y.
europepmc   +1 more source

Sliding sampling and successive variational mode decomposition CNN-BiLSTM-attention based fault detection and early warning method for DC microgrid. [PDF]

Sci Rep
Dai Y, Wang M, Zhang L, Wang S, Jiang Z.
europepmc   +1 more source