Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Multi-hop clustering routing algorithm based on fuzzy inference and multi-path tree
Wireless sensor network technologies have been widely used in modern life especially in Internet of Things. Since battery energy of sensor nodes is limited, balancing the energy consumption of each node on a transmitting path is an important issue.
Yanshan Tian +3 more
doaj +1 more source
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
A sensor node scheduling algorithm for heterogeneous wireless sensor networks
To improve the regional coverage rate and network lifetime of heterogeneous wireless sensor networks, a sensor node scheduling algorithm for heterogeneous wireless sensor networks is proposed. In sensor node scheduling algorithm, heterogeneous perception
Zhangquan Wang +5 more
doaj +1 more source
Energy-efficiency opportunistic spectrum allocation in cognitive wireless sensor network
The developments in wireless sensor network (WSN) that enriches with the unique capabilities of cognitive radio technique are giving impetus to the evolution of Cognitive Wireless Sensor Network (CWSN).
Cheng Wu, Yiming Wang, Zhijie Yin
doaj +1 more source
A Multi-Node Detection Algorithm Based on Serial and Threshold in Intelligent Sensor Networks
With the continuous progress of science and technology, intelligent wireless sensor network (IWSN) communication has become indispensable in its role in production and life because of its convenient network settings and flexible use.
Guanghua Zhang +5 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
River water-level estimation using visual sensing [PDF]
This paper reports our initial work on the extraction of en- vironmental information from images sampled from a camera deployed to monitor a river environment.
Diamond, Dermot +4 more
core +1 more source

