Results 81 to 90 of about 1,502,311 (318)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Distributed data association for multi-target tracking in sensor networks [PDF]

open access: yes, 2005
Associating sensor measurements with target tracks is a fundamental and challenging problem in multi-target tracking. The problem is even more challenging in the context of sensor networks, since association is coupled across the network, yet ...
Cetin, Mujdat   +3 more
core   +1 more source

Multi-hop Diffusion LMS for Energy-constrained Distributed Estimation

open access: yes, 2014
We propose a multi-hop diffusion strategy for a sensor network to perform distributed least mean-squares (LMS) estimation under local and network-wide energy constraints.
Hu, Wuhua, Tay, Wee Peng
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Detection and Isolation of Link Failures under the Agreement Protocol

open access: yes, 2013
In this paper a property of the multi-agent consensus dynamics that relates the failure of links in the network to jump discontinuities in the derivatives of the output responses of the nodes is derived and verified analytically.
Preciado, Victor M., Rahimian, M. Amin
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

An Embedded Multi-Agent Systems Based Industrial Wireless Sensor Network

open access: yesSensors, 2017
With the emergence of cyber-physical systems, there has been a growing interest in network-connected devices. One of the key requirements of a cyber-physical device is the ability to sense its environment.
Mohammed S. Taboun, Robert W. Brennan
doaj   +1 more source

Reconstructing diffusion fields sampled with a network of arbitrarily distributed sensors [PDF]

open access: yes, 2014
Sensor networks are becoming increasingly prevalent for monitoring physical phenomena of interest. For such wireless sensor network applications, knowledge of node location is important. Although a uniform sensor distribution is common in the literature,
Dragotti, PL, Murray-Bruce, J
core  

Home - About - Disclaimer - Privacy