Results 91 to 100 of about 106,374 (297)

A hibernating multi-swarm optimization algorithm for dynamic environments [PDF]

open access: yes2010 Second World Congress on Nature and Biologically Inspired Computing (NaBIC), 2010
Many problems in the real world are dynamic in which the environment changes. However, the nature itself provides solutions for adaptation to these changes in order to gain the maximum benefit, i.e. finding the global optimum, at any moment. One of these solutions is hibernation of animals when food is scarce and an animal may use more energy in ...
Masoud Kamosi   +2 more
openaire   +1 more source

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

Multi-target Tracking Algorithm Based on Improved Simplified Particle Swarm Optimization [PDF]

open access: yesJisuanji gongcheng, 2016
Based on the connection of occlusion problem in multi-target tracking and social interaction model,an improved Simplified particle Swarm Optimization(SSO) algorithm of multi-group social model with inter-group dynamic information is proposed,which is ...
CHENG Xianbao
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Resilient Task Allocation for UAV Swarms: A Bilevel PSO-ILP Optimization Approach

open access: yesDrones
To address the severe challenges of task allocation for UAV swarms in uncertain complex environments, this paper introduces the concept of equivalent load, constructs the load capability matrix of a single UAV and the task required load matrix of the ...
Yifan Zeng   +4 more
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Multi-criteria Evolution of Neural Network Topologies: Balancing Experience and Performance in Autonomous Systems

open access: yes, 2018
Majority of Artificial Neural Network (ANN) implementations in autonomous systems use a fixed/user-prescribed network topology, leading to sub-optimal performance and low portability.
Behjat, Amir   +2 more
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Some Experiments on Fitting of Gielis Curves by Simulated Annealing and Particle Swarm Methods of Global Optimization [PDF]

open access: yes
In this paper an attempt has been made to fit the Gielis curves (modified by various functions) to simulated data. The estimation has been done by two methods - the Classical Simulated Annealing (CSA) and the Particle Swarm (PS) methods - of global ...
Mishra, SK
core   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy