Results 121 to 130 of about 387,938 (287)

An underground coal mine multi-target detection algorithm

Gong-kuang zidonghua
Currently, underground coal mine target detection algorithms based on deep learning show poor performance in detecting complex small targets under conditions of uneven light intensity distribution, complex target environments, and imbalanced multi-class ...
FAN Shoujun, CHEN Xilin, WEI Liangyue, WANG Qingyu, ZHANG Shiyuan, DONG Fei, LEI Shaohua   +6 more
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Detection-Driven Gaussian Mixture Probability Hypothesis Density Multi-Target Tracker for Airborne Infrared Platforms [PDF]

Min Hong, Jiarong Wang, Ming Zhu, Shenyi Cao, Haitao Nie, Xiangdong Xu   +5 more
openalex   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Research on multi-scale fusion image enhancement and improved YOLOv5s lightweight ROV underwater target detection method [PDF]

Yongfa Mi, Mingshan Chi, Qiang Zhang, Pengjie Liu   +3 more
openalex   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Ultrasensitive detection of Bacillus anthracis by real time PCR targeting a polymorphism in multi-copy 16S rRNA genes and their transcripts [PDF]

, 2021
Peter Braun, Martin Duy-Thanh Nguyen, Mathias C. Walter, Gregor Grass   +3 more
openalex   +1 more source

Multi-Target Detection for Cognitive MIMO Radar Networks

In this work, we develop centralized and decentralized signal fusion techniques for constant false alarm rate (CFAR) multi-target detection with a cognitive radar network in unknown noise and clutter distributions. Further, we first develop a detection statistic for co-located monostatic MIMO radar in unknown noise and clutter distributions which is ...
Goradia, Nicholas L. K., Dhillon, Harpreet S., Buehrer, R. Michael   +2 more
openaire   +2 more sources