Results 41 to 50 of about 69,929 (304)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

PPF-Dependent Fixed Point Results for New Multi-Valued Generalized F-Contraction in the Razumikhin Class with an Application

open access: yesMathematics, 2019
In this paper, a new multi-valued generalized F-contraction mapping is given. Using it, the existence of PPF-dependent fixed point for such mappings in the Razumikhin class is obtained. Moreover, an application for nonlinear integral equations with delay
Hasanen A. Hammad, Manuel De la Sen
doaj   +1 more source

FIRST DIRECT PONTRYAGIN’S METHOD FOR DIFFERENTIAL INCLUSIONS

open access: yesМіжнародний науково-технічний журнал "Проблеми керування та інформатики", 2020
Pontryagin’s direct methods played a large role in the development t of the theory of differential games and its application to specific applied problems.
І.М. Ісканаджієв
doaj   +1 more source

On Multi-valued Weak Contraction Mappings

open access: yesJournal of Mathematics Research, 2011
In this paper, we study fixed point theorems for multi-valued weak contractions. We show that the Picard projection iteration converges to a fixed point, give a rate of convergence and generalize Collage theorem. This work includes results on multi-valued contraction mappings studied by (Kunze, H.E., La Torre, D.
Kritsana Neammanee, Annop Kaewkhao
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Cayley Inclusion Problem Involving XOR-Operation

open access: yesMathematics, 2019
In this paper, we study an absolutely new problem, namely, the Cayley inclusion problem which involves the Cayley operator and a multi-valued mapping with XOR-operation.
Imran Ali, Rais Ahmad, Ching-Feng Wen
doaj   +1 more source

Generalized dynamic process for an extended multi-valued F-contraction in metric-like spaces with applications

open access: yesAlexandria Engineering Journal, 2020
In this article, some fixed point results satisfying an extended multi-valued F-contraction mapping in the context of metric-like spaces are developed. Also, some standard examples are dressed to support our theoretical consequences. Finally, we conclude
Hasanen A. Hammad   +2 more
doaj   +1 more source

Some Common Fixed Point Theorems for Mappings and Multi-valued Mappings

open access: yesJournal of Mathematical Analysis and Applications, 1998
Let \((X,d)\) be a complete metrically convex metric space, \(K\subset X\) a nonempty closed subset of \(X\), \(F,G:K\to CB(X)\), \(S,T:K\to X\). The authors give some metric conditions which imply that there exists \(z\in K\) such that \(z= S(z)= T(z)\in F(z)\cap G(z)\).
Ahmad, Aqeel, Imdad, M.
openaire   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

A study of coupled systems of mixed order fractional differential equations and inclusions with coupled integral fractional boundary conditions

open access: yesAdvances in Difference Equations, 2020
In this work we investigate existence and uniqueness of solutions for new coupled systems of mixed order fractional differential equations and inclusions supplemented with coupled nonlocal fractional boundary conditions.
Sotiris K. Ntouyas, Hamed H. Al-Sulami
doaj   +1 more source

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