Results 81 to 90 of about 660,377 (283)
MLFLHMDA: predicting human microbe-disease association based on multi-view latent feature learning
Frontiers in MicrobiologyIntroductionA growing body of research indicates that microorganisms play a crucial role in human health. Imbalances in microbial communities are closely linked to human diseases, and identifying potential relationships between microbes and diseases can ...
Ziwei Chen +3 more
doaj +1 more source
Real-time multi-view deconvolution [PDF]
Bioinformatics, 2015 Abstract Summary: In light-sheet microscopy, overall image content and resolution are improved by acquiring and fusing multiple views of the sample from different directions. State-of-the-art multi-view (MV) deconvolution simultaneously fuses and deconvolves the images in 3D, but processing takes a multiple of the acquisition time and ...
Schmid, B., Huisken, J.
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Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
, 2018 With a plethora of data capturing modalities becoming available, the same data object often leaves different kinds of digital footprints. This naturally leads to datasets comprising the same set of data objects represented in different forms, called multi-view data.
Padmanabhan, Deepak +1 more
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Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Research of personalized recommendation system based on deep neural network
Dianzi Jishu Yingyong, 2019 The deep neural network is similar to the biological neural network, so it has the ability of high efficiency and accurate extraction of the deep hidden features of information, can learn multiple layers of abstract features, and can learn more about ...
Zi Yunfei, Li Yeli, Sun Huayan
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LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
ISPRS International Journal of Geo-Information, 2016 We have presented a framework to obtain camera pose (i.e., position and orientation in the 3D space) with real scale information of the uncalibrated multi-view images and the intrinsic camera parameters automatically.
Cailin Li, Langming Zhou, Wenhe Chen
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source