Results 131 to 140 of about 4,440,004 (198)

Single‐Cell Profiling Identifies CLEC5A+ Macrophages as Key Drivers of Thoracic Aortic Aneurysm Via CCL5‐Mediated M1 Polarization

Journal of Clinical Laboratory Analysis, EarlyView.
Thoracic aortic aneurysm (TAA) is a life‐threatening cardiovascular disease with limited therapeutic options. Through single‐cell RNA sequencing of aortic tissues from healthy individuals and TAA patients (105,541 cells), we identified CLEC5A+macrophages as the predominant pathogenic cell population exhibiting the highest M1 polarization score. Machine
Xiangyu Li, Chunguang Guo, Mingyao Luo, Chang Shu   +3 more
wiley   +1 more source

Unconventional Electron-Deficient Multicenter Bonds in AIO₃ Perovskites. [PDF]

Chem Mater
Osman HH, Rodrigo-Ramón JL, Ullah S, Bandiello E, Errandonea D, Gomis Ó, García-Sánchez T, Botella P, Oliva R, Rodríguez-Hernández P, Muñoz A, Popescu C, Alabarse FG, Manjón FJ.   +13 more
europepmc   +1 more source

Integrated Bioinformatics Analysis Identifies FCER1G, IL1R2, and BST1 as Diagnostic Biomarkers and Therapeutic Targets in Sepsis

Journal of Clinical Laboratory Analysis, EarlyView.
Integrative bioinformatics and experimental validation of FCER1G, IL1R2, and BST1 as biomarkers and therapeutic targets in neonatal sepsis. ABSTRACT Background Sepsis remains difficult to diagnose since blood culture has low sensitivity and current biomarkers lack sufficient specificity.
Junjie Li, Guanghui Xiu, Ping Liu, Xianzhong Chen, Kailv Zhou, Yunfeng Yang   +5 more
wiley   +1 more source

Effects of Substituents on 9‑Fluorenone: Spectroscopic, Hirshfeld, Optical, NLO, IFCT, and CTM Properties. [PDF]

ACS Omega
Akman F.
europepmc   +1 more source

Diagnostic Performance of Direct PCR Assay for Candida auris Detection: A Comparison of Liquid Amies Transport Medium and Fungal Enrichment Broth

Journal of Clinical Laboratory Analysis, EarlyView.
This study evaluated a direct PCR assay for rapid Candida auris screening from skin swabs using two transport media. The direct PCR assay demonstrated high sensitivity (92.0%–96.0%) and rapid turnaround time (~3 h). Liquid Amies medium showed a more favorable specificity profile, supporting its practical utility for screening.
Jung‐ah Kim, Yu Kyung Jeon, Eun Jeong Won, Heungsup Sung, Mi‐Na Kim   +4 more
wiley   +1 more source

Assessing gastroesophageal reflux disease (GERD) threat 5 years following laparoscopic vertical sleeve gastrectomy (LVSG) and laparoscopic Roux-en-Y gastric bypass (LRYGB): which measure of association is appropriate, odds ratio (OR) or relative risk (RR)? [PDF]

Transl Gastroenterol Hepatol
Memon MA, Hoque Z, Khan S, Alam K.
europepmc   +1 more source

The Landscape of Biomarkers in ICU‐Associated AKI: From Protein Markers to Cell‐Free Nucleic Acids

Journal of Clinical Laboratory Analysis, EarlyView.
Acute kidney injury (AKI) in critically ill patients—particularly in sepsis—often develops early and is missed by creatinine/urine output–based criteria, delaying risk stratification and timely intervention. This review synthesizes current evidence on established and emerging AKI biomarkers (e.g., NGAL, KIM‐1, [TIMP‐2]·[IGFBP7]) alongside circulating ...
Qi Zhu, Feng Yang, Hua Zheng, Xinxin Guo, Zhijin Chen, Limin Chen, Daoli Wang, Jiaqi Wang, Xinmeng Wang, Zhiyuan Huang, Zhenhua Ji   +10 more
wiley   +1 more source

Outcomes of tafasitamab and lenalidomide in large B-cell lymphoma based on prior CD19-directed CAR T exposure. [PDF]

Hemasphere
Merrill MH, Redd RA, Lambert N, Caimi PF, Pullarkat P, Godby RC, Bond DA, Wehmeyer GT, Romancik J, Amoozgar B, Leslie L, Nastoupil LJ, Crombie JL, Abramson JS, Khurana A, Nowakowski GS, Maddocks K, Rutherford SC, Kahl B, Okwali M, Buege MJ, Batlevi CL, Armand P, Salles G, Qualls DA.   +24 more
europepmc   +1 more source

Verification of False Reactivity in HIV Rapid Diagnostic Tests and Its Translation Into the Three Tests Algorithm in Cameroon

Journal of Clinical Laboratory Analysis, EarlyView.
Verification study enabled the detection of HIV false reactivity ranging from 0‐4% across rapid diagnostic tests. A reliable three‐tests algorithm ranked First Response HIV 1‐2‐0 Card, First Response HIV1+2/Syphilis Combo or STANDARD Q as suitable test 1 to mitigate false positive events. As countries move toward HIV elimination, implementing the three‐
Rogers Ajeh Awoh, Désiré Takou, Isidore Oscar Bienvenu Etogo Ondigui, Roger Onana, Etienne Kembou, Collins Chenwi, Daniel Mabongo, Grace Beloumou Angong, Laetitia Bissai, Aude Christelle Ka'e, Alex Durand Nka, Ezechiel Ngoufack Jagni Semengue, Nadine Fainguem, Daniele Simnoue, Florine Tsimene, Sandrine Djupsa, Jaurès Metambou, Aurelie Kengne, Arlette Messeh, Gilbert Tchatchoua, Naomi‐Karell Etame, Michel Tommo, Krystel Zam Nnomo, Edith Temgoua, Basil Yaba, Gregory Edie Halle Ekane, Carlo‐Federico Perno, Vittorio Colizzi, Nicaise Ndembi, Diaby Ousmane, Joelle Bouba Pamen, Alexis Ndjolo, Celine Lastrucci, Joseph Fokam, Malachie Manouada   +34 more
wiley   +1 more source

Hemorheological Alterations as a Driver of Microangiopathy in Diabetic Kidney Disease-The Role of Erythrocyte. [PDF]

Int J Mol Sci
Garoufis M, Kostara C, Sakkou SF, Filippas-Ntekouan S, Bairaktari E, Tsimihodimos V.   +5 more
europepmc   +1 more source