Results 131 to 140 of about 1,003,545 (313)

Clinical Features According to the Type of Intermittent Exotropia: Korean Intermittent Exotropia Multicenter Study

Epidemiologia
Background/Objectives: To determine the clinical features of different types of intermittent exotropia according to the distance and near angles of exodeviation. Methods: This study included 5331 patients with intermittent exotropia.
Hee Kyung Yang, Hae Ri Yum, Sun A Kim, Hyuna Kim, Jinu Han, Yoonae A. Cho, Hyunkyung Kim, Dong Gyu Choi   +7 more
doaj   +1 more source

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and One‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

Arthritis Care &Research, Accepted Article.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension‐phase). During part 1, three doses were assessed in two weight groups (Group A/B: ≥30–60 kg/≥10–<
Fabrizio De Benedetti, Inmaculada C. Penadés, Irina Nikishina, Ivan Foeldvari, Alberto J. Spindler, Anna Kozlova, Nadina Rubio‐Pérez, Pierre Quartier, Zbigniew Żuber, Raul Barria, Daniel Clemente, Gabriel V. Cornejo, Katherine Marzan, Nancy Liu, Christine Xu, Stephen DiMartino, Angeliki Giannelou, Fei Cao‐Ghoul, Bolanle Akinlade, Lydie Baret‐Cormel   +19 more
wiley   +1 more source

The nature of the association of IL10 gene single nucleotide polymorphisms (rs1800896 and rs1800872) with the development of primary open-angle glaucoma in patients from different regions of Russia based on the results of a multicenter study

Сибирский научный медицинский журнал
One of the development factors of primary open-angle glaucoma (POAG) is genetic predisposition to its occurrence, associated with the peculiarity of cytokine genes.
V. I. Konenkov, A. V. Shevchenko, V. F. Prokofiev, D. G. Arsyutov, N. S. Khodzhaev, E. V. Boiko, M. M. Pravosudova, A. D. Chuprov, Yu. S. Kuvaitseva, N. Yu. Gorbunova, A. A. Markova, Yu. V. Zotova, M. V. Pshenichnov, N. V. Postupaeva, Yu. V. Malysheva, A. A. Ivanov, A. V. Eremina, A. N. Trunov, V. V. Chernykh   +18 more
doaj   +1 more source

Validation of a Genetic Risk Score Combined With Clinical Variables for Predicting Pulmonary Fibrosis in Early Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective Pulmonary fibrosis (PF) is a severe extra‐articular manifestation of rheumatoid arthritis (RA). This study aimed to externally validate a genetic risk score (GRS) and a combined risk score (CRS) for predicting the risk of RA‐associated PF in an independent cohort of patients with early RA.
Mikael Brink, Austin Wheeler, Bryant R. England, Solbritt Rantapää‐Dahlqvist   +3 more
wiley   +1 more source

Severe and/or prolonged COVID-19 in hematologic diseases: clinical implications before and during the omicron era

Frontiers in Oncology
BackgroundAlthough the Omicron variant has been reported to reduce COVID-19 severity in the general population, its impact on patients with hematologic malignancies remains uncertain, and epidemiological investigation is warranted.MethodsWe conducted a ...
Akinao Okamoto, Masahiro Yoshida, Senji Kasahara, Takahide Ara, Kazutaka Ozeki, Takanobu Morishita, Takanobu Morishita, Daisuke Ikeda, Minoru Kanaya, Tomohiro Kajiguchi, Yasuhiro Suzuki, Shingo Kurahashi, Tomohiro Horio, Yoshiaki Marumo, Tatsuo Oyake, Shigeki Saito, Hitomi Sawa, Shun-ichi Kimura, Takahiro Nishiyama, Eisei Kondo, Junji Hiraga, Hiroki Hosoi, Yasufumi Masaki, Yoshiko Atsuta, Hideyuki Yamamoto, Takahiko Miyama, Naoe Goto, Chisako Iriyama, Keichiro Mihara, Yoshihiro Inamoto, Akihiro Tomita   +30 more
doaj   +1 more source

Female hormonal exposures and neuromyelitis optica symptom onset in a multicenter study [PDF]

, 2017
Alvarez, Enrique, Cross, Anne H, et al,
core   +2 more sources

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients With Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner, Jordi Antón, Inmaculada Calvo‐Penadés, Richard Dimelow, Gerd Horneff, Sylvia Kamphuis, Rebecca Marino, Andre van Maurik, Kirsten Minden, Masaaki Mori, Josephine Ocran‐Appiah, Christel Wilkinson, Yuichi Yamasaki, Deepak Assudani, for the Pediatric Rheumatology Collaborative Study Group (PRCSG) and Paediatric Rheumatology International Trials Organisation (PRINTO) Network investigators   +14 more
wiley   +1 more source

Mortality in acute type A aortic dissection – A systematic review based on contemporary registries

Romanian Journal of Internal Medicine
Acute type A aortic dissection (ATAAD) remains one of the most time-critical cardiovascular emergencies, with early mortality continuing to pose substantial clinical and organizational challenges.
Matei Diana-Cristina, Robu Cornel, Ciobanu Celia Georgiana, Geavlete Oliviana Dana, Antohi Elena-Laura, Radu RăZvan Ilie, Bubenek Șerban, Iliescu Vlad Anton, Chioncel Ovidiu   +8 more
doaj   +1 more source

Combining Three Peripheral Blood Biomarkers to Stratify Rheumatoid Arthritis‐Associated Interstitial Lung Disease Risk

Arthritis Care &Research, Accepted Article.
Objective The purpose was to evaluate a biomarker score consisting of MUC5B rs35705950 promoter variant, plasma matrix metalloproteinase (MMP)‐7, and serum anti‐malondialdehyde‐acetaldehyde (anti‐MAA) antibody for RA‐associated interstitial lung disease risk stratification. Methods Using a multicenter cohort of US veterans with RA, we performed a cross‐
Kelsey Coziahr, Austin M. Wheeler, Brent A. Luedders, Michael Duryee, Halie Frideres, Katherine D. Wysham, Grant W. Cannon, Gary Kunkel, Dana P. Ascherman, Paul A. Monach, Gail S. Kerr, Andreas M. Reimold, Scott M. Matson, Joshua F. Baker, Geoffrey M. Thiele, Ted R. Mikuls, Bryant R. England   +16 more
wiley   +1 more source

Guidelines-based therapeutic strategies for controlling hypertension in non-controlled hypertensive patients followed by family physicians in primary health care in Portugal: the GPHT-PT study

Blood Pressure
Purpose In a prospective open study, with intervention, conducted in Primary Health Care Units by General Practitioners (GPs) in Portugal, the effectiveness of a single pill of candesartan/amlodipine (ARB/amlodipine), as the only anti-hypertension (anti ...
Jorge Polónia, Raul Marques Pereira
doaj   +1 more source