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Coffin‐Lowry syndrome: a multicenter study
Clinical Genetics, 1988The Coffin‐Lowry syndrome is an inherited syndrome of mental retardation, characteristic facies and skeletal anomalies. The occurrence of severe manifestations in males, with no instance of male‐to‐male transmission, suggests an X‐linked inheritance. The paper describes seven families from five European Centers.
S. Gilgenkrantz +12 more
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A multicenter study of oral sarcomas in Brazil
Oral Diseases, 2019AbstractObjectivesThe aim of this study was to investigate the prevalence of oral sarcomas from geographic regions of Brazil.Materials and methodsA cross‐sectional study was conducted on biopsies obtained from January 2007 to December 2016 at twelve Brazilian oral and maxillofacial pathology centres.
Waldner Ricardo Souza de Carvalho +27 more
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Proximal row carpectomy: A multicenter study
The Journal of Hand Surgery, 1993Twenty patients underwent proximal row carpectomy and were retrospectively evaluated for pain, motion, grip strength, functional activity, and x-ray changes at a mean follow-up of 3 1/2 years. For nonrheumatoid patients, motion decreased 15% after surgery, mean grip strength improved 22%, and 82% believed their conditions were improved and said they ...
R W, Culp +5 more
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Dynamic cervical stabilization: a multicenter study
European Spine Journal, 2015The dynamic cervical implant (DCI) is a novel motion-preserving concept for the treatment of degenerative cervical disorders. The aim of this prospective clinical study was to validate the concept and analyse clinical and radiological performance of the implant.One hundred seventy-five consecutive patients with degenerative cervical disorders, median ...
Guy, Matgé +4 more
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Infliximab-induced autoantibodies: a multicenter study
Clinical Rheumatology, 2015The purpose of this study was to assess autoantibody incidence in patients treated with infliximab for various diseases, and the development of autoimmune diseases using a multicenter, longitudinal, open-label, phase IV observational study. All patients received anti-tumor necrosis factor (anti-TNF) according to local treatment guidelines.
João Luiz Pereira, Vaz +4 more
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Adjustments for Center in Multicenter Studies: An Overview
Annals of Internal Medicine, 2001Increasingly, investigators rely on multicenter or multigroup studies to demonstrate effectiveness and generalizability. Authors too often overlook the analytic challenges in these study designs: the correlation of outcomes and exposures among patients within centers, confounding of associations by center, and effect modification of treatment or ...
A R, Localio +3 more
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The Norwegian multicenter study.
The American journal of medicine, 1987The largest multicenter, double-blind trial comparing piroxicam with naproxen in the treatment of osteoarthritis has recently been conducted in Norway. More than 2,000 patients were enrolled in the 12-week study. Both drugs showed similar efficacy, and serious gastrointestinal side effects occurred in less than 1 percent of the patients taking either ...
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Multicenter studies and harmonization: Problems, solutions, and open challenges
Combining diffusion magnetic resonance imaging (dMRI) across scanners and sites can improve our understanding of the human brain in health and disease, but variability in the data challenges the joint analysis of different datasets. This chapter focuses on the sources of variability in multicenter studies, solutions that have been proposed to deal withTax, Chantal M.W. +6 more
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Harmonization Strategies in Multicenter MRI-Based Radiomics
Journal of Imaging, 2022Manolis Tsiknakis +2 more
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