Results 121 to 130 of about 5,374,113 (306)

A Catalytic Osmium Redox Couple Collapses Cancer Redox Balance

Advanced Science, EarlyView.
A stable Os(III)/Os(IV) redox couple is developed to disrupt the tumor cell redox balance by concurrently catalyzing ROS generation and GSH depletion. Osmium‐treated cells exhibit multiple cell death pathways, including apoptosis, ferroptosis, and immunogenic cell death.
Wan‐Qiong Huang, Tao Huang, Yiming Hao, Gui‐Feng Huang, Yi‐Lang Yan, Xin Fang, Ying Chen, Xiao‐Long Wei, Wai‐Lun Man, Wen‐Xiu Ni   +9 more
wiley   +1 more source

Piperazine scaffolds via isocyanide-based multicomponent reactions

, 2010
Piperazine scaffolds are amongst the most extensively used backbones in medicinal chemistry and many bioactive compounds are built upon this template.
Dömling, Alexander, Yijun Huang, Huang, Yijun, Alexander Dömling   +3 more
core   +1 more source

A Bone Marrow–Mimetic Hydrogel Enables Dual‐Phase Hemostasis and Vascularized Osteogenesis for Cranial Defects

Advanced Science, EarlyView.
A biomimetic, fiber‐reinforced hydrogel (FE‐PDA@Fib/Gel‐TG) that enables dual‐phase cranial defect repair. The system provides: instant hemostasis in the early stage, and sustained co‐delivery of pro‐angiogenic and osteogenic signals for synergistic vascularized bone regeneration.
Lingbin Che, Donghong Li, Huan Zhang, Tingting Xu, Juhan Li, Xuanzhou Chen, Louis D. Zhang, Shuguang Wang, Dianwen Song, Dongyong Sha   +9 more
wiley   +1 more source

Editorial: Isocyanide-Based Multicomponent Reactions

Frontiers in Chemistry, 2020
Jonathan G. Rudick, Shabnam Shaabani, Alexander Dömling   +2 more
doaj   +1 more source

Hierarchical Ordering Induced Ultrahigh Cryogenic Strength and Strain Hardening in a Ni2CoFeV Medium‐Entropy Alloy

Advanced Science, EarlyView.
A tri‐phase Ni2CoFeV medium‐entropy alloy with fcc, κ, and L12 phases achieves exceptional cryogenic strength‐ductility synergy at 77 K. It delivers a yield strength of 1.4 GPa, an ultimate tensile strength of 2.07 GPa and a tensile ductility of 28%.
Lei Gu, Wei Jiang, Qingzhong Mao, Xiang Chen, Yonghao Zhao   +4 more
wiley   +1 more source

Organocatalytic enantioselective multicomponent reactions (OEMCRs)

, 2007
The achieved level of expertise in organocatalytic processes has allowed synthetic chemists to apply this useful synthetic strategy to enantioselective multicomponent reactions.
Guillena, Gabriela, Diego J. Ramon, Gabriela Guillena, Yus, Miguel, Ramón, Diego J., Miguel Yus   +5 more
core   +1 more source

Tailored Synthesis of Doped Non‐Layered Oxide Nanosheets Using Designed Solid‐State Surfactants

Advanced Science, EarlyView.
This work reports a solid‐state surfactant templating method that enables precise doping of non‐layered oxide nanosheets. Using ceria and rare‐earth elements as model systems, we established design principles for solid‐state surfactants containing multiple elements.
Kentaro Ito, Eisuke Yamamoto, Kohei Hayashi, Daiki Kurimoto, Makoto Kobayashi, Minoru Osada   +5 more
wiley   +1 more source

A High‐Entropy Strategy for Chemoresistive Ethanol Sensors With Remarkably Rapid and Selective Response

Advanced Science, EarlyView.
The configurational‐entropy strategy enables rapid and sensitive ethanol detection using a multicomponent oxide. The high‐entropy (InSnFeZnW)Ox provides enriched oxygen vacancies and diverse adsorption sites that strengthen surface reactivity. The sensor achieves a 5135% ethanol response with fast kinetics and stable long‐term operation.
Gi Baek Nam, Jin Ho Seo, Youngmin Kim, Hyuk Jin Kim, Yeong Jae Kim, Seon Ju Park, YunKyung Kim, Hyeon‐Min Yu, Jiwoo Lee, Ji Hyeon Lim, Jiheon Lim, Jong Hun Kang, WooChul Jung, Jong Jin Jung, Jeong Woo Han, Seung Eon Moon, Seong Ju Hwang, Jong‐Hoon Kang, Zhigang Zhu, Ho Won Jang   +19 more
wiley   +1 more source

Beyond d‐Band Catalysis: A Critical Review and Descriptor Framework for Rare‐Earth Engineering in Lithium–Sulfur Batteries

Advanced Science, EarlyView.
Rare‐earth catalysts regulate lithium–sulfur battery chemistry through f‐orbital–mediated interactions, enabling simultaneous polysulfide adsorption and catalytic conversion on conductive carbon hosts. This synergistic control suppresses the shuttle effect, accelerates redox kinetics, and guides stable Li2S nucleation, providing a mechanistic framework
Fan Wang, Shihzad Shakil, Guozhi Wu, Jiarui Huang, Hanhui Lei, Terence Xiaoteng Liu   +5 more
wiley   +1 more source

Chemo-differentiating ABB' multicomponent reactions. Privileged building blocks

, 2007
8 pages, 5 figures, 12 schemes.-- PMID: 17325787 [PubMed].-- Avaiolable online Oct 16, 2006.Multicomponent reactions (MCRs) designated as ABB are defined as those reactions that introduce into the final product one molecule of component A and two ...
Fernando Garcia‐Tellado, Tejedor, David, García-Tellado, Fernando, David Tejedor   +3 more
core   +1 more source