In order to explore the structural changes and products of histamine degradation by multicopper oxidase (MCO) in Lactiplantibacillus plantarum LPZN19, a 1500 bp MCO gene in L. plantarum LPZN19 was cloned, and the recombinant MCO was expressed in E.
Huijie Pei +15 more
doaj +2 more sources
Functional and structural insights into the multicopper oxidase MmcO from Mycobacterium tuberculosis: implications for drug targeting [PDF]
Mycobacterium tuberculosis (Mtb) is a significant and highly pathogenic intracellular microorganism responsible for tuberculosis (TB). The global TB crisis has been exacerbated by the emergence and spread of multidrug-resistant Mtb strains, resulting in ...
Dafeng Liu +4 more
doaj +2 more sources
Screening and Characterization of Lactiplantibacillus plantarum WYP with Histamine-Degrading Activity: A Probiotic Candidate Assessed Based on Phenotyping Experiments and Whole-Genome Sequencing [PDF]
This study isolated and characterized Lactiplantibacillus plantarum WYP from naturally fermented pineapple peel residues. The strain exhibited a potent in vitro histamine degradation rate of 78.63% and demonstrated multiple probiotic properties ...
Yaping Wang +5 more
doaj +2 more sources
Mechanistic Investigations into the Selective Reduction of Oxygen by a Multicopper Oxidase T3 Site-Inspired Dicopper Complex. [PDF]
Understanding how multicopper oxidases (MCOs) reduce oxygen in the trinuclear copper cluster (TNC) is of great importance for development of catalysts for the oxygen reduction reaction (ORR).
van Langevelde PH +5 more
europepmc +2 more sources
A novel multicopper oxidase (laccase) from cyanobacteria: Purification, characterization with potential in the decolorization of anthraquinonic dye. [PDF]
A novel extracellular laccase enzyme produced from Spirulina platensis CFTRI was purified by ultrafiltration, cold acetone precipitation, anion exchange and size exclusion chromatography with 51.5% recovery and 5.8 purification fold. The purified laccase
Sumbul Afreen +7 more
doaj +2 more sources
Identification and characterization of two novel Acinetobacter species capable of degrading polyester [PDF]
The ubiquitous presence of Acinetobacter species in the environment holds significant biotechnology potential, particularly in the degradation of various pollutants. In this study, we characterize two plastic-degrading bacteria, strains CAAS 2-6 and CAAS
Mengli Xia +6 more
doaj +2 more sources
Identification and Characterization of a Polyethylene-Degrading Fungus Aspergillus sydowii Isolated from Soils of Waste Disposal Sites [PDF]
Petrochemical-based plastics are widely used due to their convenience and low cost, with polyethylene (PE) being the most produced globally. However, the lack of efficient and sustainable treatment methods for conventional plastic wastes has led to ...
Qingyue Wang +4 more
doaj +2 more sources
Identification and Characterization of a Novel Plasmid-Encoded Laccase-Like Multicopper Oxidase from Ochrobactrum sp. BF15 Isolated from an On-Farm Bio-Purification System. [PDF]
SUMMARY Research background In recent decades, laccases (p-diphenol-dioxygen oxidoreductases; EC 1.10.3.2) have attracted the attention of researchers due to their wide range of biotechnological and industrial applications. Laccases can oxidize a variety
Martini MC +9 more
europepmc +2 more sources
Role of the Multicopper Oxidase CueO in Copper Homeostasis Under Anaerobic Conditions in Enterobacteria. [PDF]
The periplasmic multicopper oxidase CueO plays a crucial role in copper detoxification in enterobacteria. CueO contains a catalytic site, the Cu‐T1 center, and a methionine‐rich (Met‐rich) domain capable of binding copper.
Becam J +4 more
europepmc +2 more sources
Transient Absorption Spectroscopy of Blue Copper Sites in Divergent Protein Folds: Azurin Versus Multicopper Oxidase. [PDF]
Ultrafast pump‐probe spectroscopy of two evolutionarily divergent blue copper proteins reveals distinct low‐frequency ground‐state collective modes (38 cm−1 in SLAC, 29 cm−1 in azurin) generated via impulsive stimulated Raman scattering, potentially reflecting the differences in the rigidity of the surrounding protein scaffold beyond a conserved Cu ...
Domenianni LI, Kielb P.
europepmc +2 more sources

